Ewan McGregor and Charley Boorman, after more than a decade since their last motorbike adventure around the world, will cover 13,000 miles over 100 days through 13 countries. Starting from the city of Ushuaia at the tip of South America, Ewan and Charley travel through the glorious and underexposed landscapes of South and Central America to Los Angeles in the United States in their most challenging expedition to date. In their journey they will use cutting-edge technology on the backs of their prototype electric Harley-Davidsons in order to contribute to the sustainability of the planet.
In the first episode, Ewan McGregor reunites with his best friend Charley Boorman to evaluate what's important in their lives, following a life-threatening accident of Charley.

Ewan, Charley, and the team land in Ushuaia, the southernmost tip of South America, but tensions arise due to snow and mechanical issues. Traveling 13000 miles over 100 days on electric bikes is hard to imagine. Ewan McGregor and Charles Boorman find out how challenging their mission is as they embark on a journey on prototype Harley Davidsons and the Rivian trucks. The first obstacle is electricity. While parts of the city have no problems with charging the bikes and the trucks, the countryside is where the duo face issues.