Join investigators as they untangle the cause of Alzheimer’s and race to develop a cure. Alzheimer’s disease strikes at the core of what makes us human: our capacity to think, to love, and to remember. The disease ravages the minds of over 40 million victims worldwide, and it is one of the greatest medical mysteries of our time. Join investigators as they gather clues and attempt to reconstruct the molecular chain of events that ultimately leads to dementia". Follow key researchers in the field who have helped to develop the leading theories of the disease. Along the way, meet individuals from all walks of life who will reveal what it’s like to struggle with Alzheimer’s. Among them, members of a unique Colombian family who have learned that their genetic predisposition all but guarantees early onset Alzheimer’s. Yet there may be hope. Join these courageous patients participating in clinical trials, and then go behind the scenes of the major drug trials to see how researchers target and test therapies that may slow and even prevent Alzheimer’s

The Sky at Night looks back at the last ten years of astronomy and ponders the most significant milestones and revelations. With the help of six distinguished astronomers, Chris and Maggie consider the state of astronomy in 2020 and wonder what new, exciting discoveries await us across the rest of the decade, as a host of new ground and space telescopes come online. Astronomer Royal Lord Martin Rees is among the guests to walk along the Astronomical Wall of Discovery in this one-hour special.

The sun gives us warmth and light. It is the fuel of life. Without the energy of the sun almost nothing grows, thrives or lives. But the sun was not put there for our benefit. It is not this big jolly ball of nice smiling down on us, wishing us all a good day. It is not our friend. The sun is a monster. A planet killer. And we don't see that side of the sun down here.
But eight astronauts, with over 1,000 days in space between them, can show us how being up there helped them understand the suns bright fury.

25 years ago, NASA launched one of the most ambitious experiments in the history of astronomy: the Hubble Space Telescope. In honor of Hubble's landmark anniversary, know the remarkable story of the telescope that forever changed our understanding of the cosmos and our place in it". But amazingly, when the telescope first sent images back to earth, it seemed that the entire project was a massive failure; a one-millimeter engineering blunder had turned the billion-dollar telescope into an object of ridicule. It fell to five heroic astronauts in a daring mission to return Hubble to the cutting edge of science. Hear from the scientists and engineers on the front line who tell the amazing Hubble story as never before. This single telescope has helped astronomers pinpoint the age of the universe, revealed the birthplace of stars and planets, advanced our understanding of dark energy and cosmic expansion, and uncovered black holes lurking at the heart of galaxies. For more than a generation, Hubble's stunning images have brought the beauty of the heavens to millions, revealing a cosmos richer and more wondrous than we ever imagined. Join us for the story of this magnificent machine and its astonishing discoveries.

Tony Accardo receives a phone call from Joseph P. Kennedy, asking the mob kingpins to use their pull with the Illinois union vote to help his son, John F. Kennedy, win the upcoming presidential election. In return, he offers to put an end to his son Robert F. Kennedy's investigation into Giancana and the Outfit. As election day nears, Kennedy's fight against Richard Nixon tightens, turning Illinois into a key battleground. Giancana delivers the union votes. After a close race, Kennedy is declared the victor. Just weeks after Kennedy takes office, his brother Robert is named Attorney General. To the Chicago mob's surprise, when Robert takes office as the new U.S. Attorney General in 1961, he makes his top priority going after organized crime ó and one of his primary targets is the Outfit. Weeks after, John F. Kennedy is shot and killed in Dallas. After his brother is assassinated, Robert steps down from his post as Attorney General and the investigation into organized crime is virtually dropped. The government begins an investigation into the assassination, with rumors already circulating that the mafia could have been involved.

Al-Khalili travels to northern Syria to discover how, a thousand years ago, the great astronomer and mathematician Al-Biruni estimated the size of the earth to within a few hundred miles of the correct figure. He discovers how medieval Islamic scholars helped turn the magical and occult practice of alchemy into modern chemistry. In Cairo, he tells the story of the extraordinary physicist Ibn al-Haytham, who helped establish the modern science of optics and proved one of the most fundamental principles in physics - that light travels in straight lines. Prof Al-Khalili argues that these scholars are among the first people to insist that all scientific theories are backed up by careful experimental observation, bringing a rigour to science that didn't really exist before.