Destiny is beyond our control, our fate already set, perhaps from the onset of disease or being born with a special ability. You may think our lives are determined by the genes we're born with, but that is not the case. In the non-coding 98% of our DNA, we have countless switches to promote or suppress the physiological reactions of our bodies. Interestingly, we can change the states of these switches through our own efforts and even can affect the DNA conditions of our offspring before their birth.
Explore the hottest area of bioscience, genomics with stunning live image, quality CGI, the forefront research, and real human stories.

In this final episode, Mary Beard delves even deeper into ordinary Roman life by going behind the closed doors of their homes. She meets an extraordinary cast of characters - drunken housewives, teenage brides, bullied children and runaway slaves - and paints a more dynamic, lusty picture of Roman family life. Mary uncovers their preserved beds, furniture and cradles, tries on Roman wedding rings and meets some eccentric wives like Glyconis, praised by her husband for liking a drink or two, and Allia Potestas, who lived in a Roman menage a trois. Mary explores Roman parenting, childbirth and children, including Sulpicius Maximus, an 11-year-old schoolboy who was worked to death by his pushy parents, and Geminia Mater, a 5-year-old tomboy. Finally, Mary paints a more nuanced picture of Roman slavery and asks why if it was such a brutal institution did many Romans choose to be buried with their servants - living cheek by jowl in death, as in life

In the fourth part of the series, Diarmaid MacCulloch makes sense of the Reformation, and of how a faith based on obedience and authority gave birth to one based on individual conscience. He shows how Martin Luther wrote hymns to teach people the message of the Bible, and how a tasty sausage became the rallying cry for Swiss Reformer Ulrich Zwingli to tear down statues of saints, allow married clergy and deny that communion bread and wine were the body and blood of Christ.

The film reveals the secret story behind one of the greatest intellectual feats of World War II, a feat that gave birth to the digital age.
In 1943 Bill Tutte, a 24-year-old maths student and a GPO engineer called Tommy Flowers combined to hack into Hitler's personal super code machine - not Enigma but an even tougher system, which he called his 'secrets writer'. Their break turned the Battle of Kursk, powered the D-day landings and orchestrated the end of the conflict in Europe. But it was also to be used during the Cold War - which meant both men's achievements were hushed up and never officially recognised.

Painted over five centuries ago, Filippo Lippi's nativity is like none other: it shows the birth of Christ in a dark, wooded wilderness. There are no shepherds, kings, ox, ass – there is no Joseph. Its beauty inspired Michelangelo, Leonardo da Vinci and Botticelli. But it also conceals a deeply personal story. It was painted for Cosimo de Medici, a wealthy banker who feared that his money was dragging him straight to hell. The artist's life was equally surprising. One of the most celebrated painters of his day, Filippo Lippi was also a Carmelite friar, but he was no stranger to the temptations of the flesh, to which he frequently yielded. Shortly before painting his Adoration, he caused uproar by seducing a twenty year-old nun. His paintings rejoice not only in divine beauty, but in the beauty of women. In later times, the Adoration's history was interwoven with that of rulers and dictators. It became a bargaining chip after Napoleon's allies seized twenty merchant ships. And in the 20th century, it was hidden by the Nazis in a potassium mine, where specialist american officers, known as Monuments Men, stumbled upon it. they were now told to get it ready to be shipped out. In an unprecedented turn of events they refused. This is the only known case in the whole of the Second World War of American officers refusing an order. It was sent to the National Gallery of Art, but in 1949 Lippi's Adoration was returned to Germany.

From the Philippines to the US, Madagascar and Mexico, Professor Brian Cox explores the globe to reveal how a few fundamental laws of science gave birth to the most complex and unique feature of the universe - life. In the first episode, Brian journeys to the volcanic landscapes of South-East Asia, seeking to understand how life first began and how that spark has endured to this day.