Horizon investigates the idea that the best way to lose weight successfully is a personalised approach, diets tailored to our individual biology and psychology. In a groundbreaking experiment, Dr Chris van Tulleken and Tanya Byron join a team of experts to put 75 overweight volunteers on diets designed to tackle the specific reasons why they eat too much. The volunteers are put through a series of tests at a residential clinic to understand how their genes, hormones and psychology influence their eating behaviour. They are then put on the diets the experts believe are best suited to them. Can science succeed where other diets have failed?

The Southern Ocean, which circles the globe without being blocked by land, is home to the Antarctic Circumpolar Current (ACC), the longest of the world's ocean currents. Also known as the "channel", it connects the Indian, Atlantic and Pacific Ocean basins and exerts a powerful influence over the Earth's climate. The ACC carries 150 times more water around Antarctica than the flow of all the world's rivers combined.

The sparkling blue waters of the Mediterranean Sea are home to over 700 varieties of fish and almost 10 per cent of the world's marine species. Its coastline is one of the most densely populated in the world and the human pressure on this sea is magnified each summer with the influx of holiday makers. Western civilisation developed around these shores but now human activity is having a profound effect on this endangered sea.