Ideas about time and space are explored in the changes that constellations undergo over time, the redshift and blue shift measured in interstellar objects, time dilation in Albert Einstein's theory of relativity, the designs of both Leonardo da Vinci and spacecraft that could travel near light speed, time travel and its hypothetical effects on human history, the origins of the Solar System, the history of life, and the immensity of space. In Cosmos Update, the idea of faster-than-light travel by wormholes (researched by Kip Thorne and shown in Sagan’s novel Contact) is discussed.

Anthropologist Wade Davis and river advocate Robert F. Kennedy Jr journey down the Colorado River on a two-week expedition to highlight water conservation issues. Traveling by rafts, kayaks and wooden dories, they are accompanied by their daughters and guided by Shana Watahomigie, a Native American National Park ranger. Filmed with a 350-pound 3D camera, it involved the cooperation of three Indian nations, the National Park Service, film sponsor Teva’s team of kayakers and more than a dozen experienced river guides. The film explores America's drought and freshwater shortages, the impact on the river of damming, and human water supply needs. Grand Canyon Adventure: River at Risk was directed by Greg MacGillivray and narrated by Robert Redford.

Professor Jim Al-Khalili sets out to discover whether nuclear power is safe. He begins in Japan, at the former Fukushima nuclear plant, where he meets some of the tens of thousands of people who have been evacuated from the exclusion zone. He travels to an abandoned village just outside the zone to witness a nuclear clean-up operation. Jim draws on the latest scientific findings from Japan and from the previous explosion at Chernobyl to understand how dangerous the release of radiation is likely to be and what that means for our trust in nuclear power.

Fancisco Pizarro hoped to find great riches in the land of the Inca when he set off on his third voyage to the new world in 1527. Travel back in time with Michael Wood and learn how Pizarro ransomed the life of a king for a room full of gold and silver. Trough letter and drawings from the 16th century and film from modern-day south America, discover this remarkable story of greed, faith, dishonor and valor.

In this episode he traces India in the days of the Roman Empire. In Kerala the spice trade opened India to the world, whilst gold and silk bazaars in the ancient city of Madurai were a delight for visiting Greek traders. From the deserts of Turkmenistan Michael travels down the Khyber Pass to Pakistan to discover a forgotten Indian Empire that opened up the Silk Route and at Peshawar built a lost Wonder of the World.

Following the Yangtze along Tiger Leaping Gorge into Yunnan in China, Palin reaches the easternmost end of the Himalayas. He gets a medical check-up before exploring medieval Lijiang with the director of the local orchestra. Heading over Myanmar to Nagaland in India he rides the steam train to Tipong Coalmine. In Assam he rides an elephant and then stays in a strange monastery.