Atheist and scientist Richard Dawkins visits England, America and Israel interveiwing prominant people of faith; Islamic, Hasidic Jews, and the new Christian sects popping up throughout the world, and expressing his view of the extent to which this fanaticism has degraded our civilisation, and will continue to degrade it. "The God Delusion" explores the unproven beliefs that are treated as factual by many religions and the extremes to which some followers have taken them. Dawkins opens the programme by describing the "would-be murderers ... who want to kill you and me, and themselves, because they're motivated by what they think is the highest ideal." Dawkins argues that "the process of non-thinking called faith" is not a way of understanding the world, but instead stands in fundamental opposition to modern science and the scientific method, and is divisive and dangerous.

In the second episode of the series, Morgan Freeman looks into prophecies of violent cataclysms, and the strife of ages past, in an attempt to determine how the world will end.

The most famous – and perhaps most misunderstood – episodes in the epic history of the Holy Wars that are known to history as The Crusades – the clash between Richard the Lionheart and Saladin. In July 1192, Richard the Lionheart stood poised for a strike on Jerusalem, while Saladin – mighty sultan of Islam – readied his troops inside the city, preparing for the inevitable attack. During a year-long campaign across Palestine, these two legendary leaders had fought each other to a stand-still. Thousands had perished, appalling atrocities had been perpetrated on both sides. And now they faced each other in a battle for their sacred objective.

Dr. Thomas Asbridge explains how in the thirteenth century, after almost two hundred years of Holy Wars, the titanic conflict between Christianity and Islam, known to history as The Crusades, reached a decisive and shocking conclusion – a chapter that despite its drama has been virtually forgotten. He explains how, in the end, the fate of the Holy Land was decided not on the hallowed ground of Jerusalem, but in Egypt; and how the ultimate outcome of the Crusades was dictated not by Christians, but by the Mongol successors to Genghis Khan, and by a Muslim slave – a fearsome warrior whose story is now all but lost to western history.

Al-Khalili travels to northern Syria to discover how, a thousand years ago, the great astronomer and mathematician Al-Biruni estimated the size of the earth to within a few hundred miles of the correct figure. He discovers how medieval Islamic scholars helped turn the magical and occult practice of alchemy into modern chemistry. In Cairo, he tells the story of the extraordinary physicist Ibn al-Haytham, who helped establish the modern science of optics and proved one of the most fundamental principles in physics - that light travels in straight lines. Prof Al-Khalili argues that these scholars are among the first people to insist that all scientific theories are backed up by careful experimental observation, bringing a rigour to science that didn't really exist before.

In the last episode, Al-Khalili turns detective, hunting for clues that show how the scientific revolution that took place in the 16th and 17th centuries in Europe had its roots in the earlier world of medieval Islam. He travels across Iran, Syria and Egypt to discover the huge astronomical advances made by Islamic scholars through their obsession with accurate measurement and coherent and rigorous mathematics.He then visits Italy to see how those Islamic ideas permeated into the west and ultimately helped shape the works of the great European astronomer Copernicus, and investigates why science in the Islamic world appeared to go into decline after the 16th and 17th centuries, only for it to re-emerge in the present day. Al-Khalili ends his journey in the Royan Institute in the Iranian capital Tehran, looking at how science is now regarded in the Islamic world