The drug policies have remained unchanged over the last 40 years so should they be reformed in the light of new research? Recent research has analysed the link between the harmful effects of drugs relative to their current classification by law with some startling conclusions. Perhaps most startling of all is that alcohol, solvents and tobacco (all unclassified drugs) are rated more dangerous than ecstasy, 4-MTA and LSD (all class A drugs).

Are the wealthy just born in the right place at the right time? Are the poor victims of a system designed to keep them down? Or do physics and biology determine who is rich and who is poor? Throughout history, distribution of wealth is governed by hidden forces: DNA, environmental stress, patterns of human migration and even the laws of thermodynamics! Nature seems to demand winners and losers in life. But does this mean greed is king, and the rich can take what they want? Or is cooperation – between microorganisms, monkeys, and humans – more essential to survival of a species?

Horizon explores the strange and wonderful world of illusions – and reveals the tricks they play on our senses and why they fool us. We show how easy it is to trick your sense of taste by changing the colours of food and drink, explain how what you see can change what you hear, and see just how unreliable our sense of colour can be. But all this trickery has a serious purpose. It’s helping scientists to create a new understanding of how our senses work – not as individual senses, but connected together. It holds the intriguing possibility that one sense could be mapped into another.

Dr Michael Mosley and Professor Alice Roberts investigate if male and female brains really are wired differently. New research suggests that the connections in men and women's brains follow different patterns, patterns which may explain typical forms of male and female behaviour. But are these patterns innate, or are they shaped by the world around us?" Using a team of human lab rats and a troop of barbary monkeys, Michael and Alice test the science and challenge old stereotypes. They ask whether this new scientific research will benefit both men and women - or whether it could drive the sexes even further apart.

Your brain is like a hungry sponge. It's constantly absorbing information. It thrives when stimulated. Between smartphones and books, and movies, and friends and family, thousands of sensations are constantly going into our heads. But what if it all got cut off?. Imagine being confined to a 10-by-10-foot room in complete isolation. No timekeeping devices, no phones, no books, nothing to write on, no windows. Psychologists say that fewer than three days in a room like this can lead to brain damage. I will be staying in this room for three days.
Michael explores the effects of isolation on the human mind by subjecting himself to a very interesting experiment.

Genetic breakthroughs have shed light on how life evolves in real-time. From filling in the missing links to creating a new species, in the last 50 years scientists have solved some of the biggest mysteries of evolution. In this episode, we look at revolutionary discoveries that shook the world and may shape our future.