Of all the diseases that plague humankind, malaria has put up one of the longest, toughest fights. More than 200 million people fall ill and 600,000 die of it every year, making it among the world’s deadliest diseases. The vast majority of those fatalities are young children - an average of one child every minute. But medical science may now be at an exciting turning point. Filmed with intimate access to key scientists on four continents, this documentary tells the inside story of the development of a new malaria vaccine that could change the very nature of the fight. It's hoped that the vaccine, dubbed R21/Matrix-M and developed by many of the same team behind the Oxford/AstraZeneca Covid-19 vaccine, will be the first to meet the World Health Organization’s target of 75 per cent efficacy.
The Beatles continue recording as the deadline for completing the project, caused by Ringo Starr's filming schedule for The Magic Christian, approaches. McCartney continues to hope that the band will perform live for an audience and Lennon meets American businessman Allen Klein for the first time. On the penultimate day, the Beatles perform an unannounced concert on the roof of the Apple Corps building, attracting crowds of passers-by as well as the attention of the Metropolitan Police.
This documentary series charting the visual appeal and historical meaning of maps. The Hereford Mappa Mundi, the largest intact Medieval wall map in the world, its ambition to picture all of human knowledge in a single image is breathtaking. The work of a team of artists, the world it portrays is overflowing with life, featuring Classical and Biblical history, contemporary buildings and events, animals and plants from across the globe, and the infamous 'monstrous races' which were believed to inhabit the remotest corners of the Earth.
As almost all animal inhabitants of Antarctica are forced to migrate north, the sea underneath the frozen ice still provides a home to many specially adapted fish whose cells are protected from freezing through an 'antifreeze' liquid. Many of them feed on the faeces of other animals. The most notable larger animal that does not migrate north is perhaps the Weddell Seal, which can be found as close as 1300 kilometres to the pole. Groups of seals tear holes into the ice to dive for food and come up to breathe. The females come back to the ice to give birth. This episode also describes primitive plant life such as lichen, which can still be found on the continent in winter, even in the extremely dry and permanently frozen valleys conditions under which dead animals can lie frozen for many centuries without decomposing. It details the life of the Emperor Penguin, 'the only birds to lay their eggs directly on ice'. While other animals retreat, Emperors migrate not just to the ice, but into the Antarctic continent. The females lay eggs which are incubated by the males under the harshest conditions on Earth (huddling closely together for warmth), while the females return to the sea.
In an enthralling documentary, Dan Snow and archaeologist Raksha Dave delve into the catastrophic impact of the Black Death on Britain 700 years ago, a pandemic that extinguished around half of the population, or three million people. The duo embarks on a journey to trace the origins and merciless spread of the plague, starting from its arrival on Britain's South coast in June 1348, through the bustling trade routes that brought the disease to Melcombe Regis, Dorset. Their investigation takes them to various hotspots of the outbreak, including the Old Operating Theatre in London and Wildwood Animal Sanctuary in Kent, where they explore the role of rats in dispersing the bubonic plague. Through dramatic reconstructions and visits to places like Nottingham University's biomedical laboratories, they uncover the rapid spread and deadly impact of the plague, offering a month-by-month account of how it ravaged the country, decimating cities, towns, and villages alike. The documentary not only showcases the horrific symptoms and desperate attempts at cures through brutal medical practices of the time but also leverages cutting-edge research to explain why the Black Death remains the deadliest pandemic in history. The personal stories of victims, from princes to paupers, are brought to light, revealing the indiscriminate nature of the disease. Dan's visit to Canterbury Cathedral and Raksha's investigation into the recent discovery of mass graves beneath a tranquil London square underline the widespread desperation and devastation. Their journey through the history of the Black Death, culminating in the discovery of its indiscriminate toll and the unveiling of mass graves in London, not only sheds light on the darkest chapters of British history but also ignites a profound understanding of the tragedy, making a compelling case for why this documentary is a must-watch for anyone interested in the profound impacts of pandemics on human society.
Not an animal, nor a plant, nor fungi, the blob is one giant single cell whose amazing capacities are leading pioneer scientists to a very new world – that of brainless intelligence. More commonly known as slime mould, this extraordinary one-billion-year-old organism challenges our understanding in many different fields. This fascinating documentary follows top experts from Europe, Japan and the US on a scientific investigation into this most surprising organism.
Filmed with intimate access to key scientists on four continents, this documentary tells the inside story of the development of a new malaria vaccine that could change the very nature of the fight. It's hoped that the vaccine, dubbed R21/Matrix-M and developed by many of the same team behind the Oxford/AstraZeneca Covid-19 vaccine, will be the first to meet the World Health Organization’s target of 75 per cent efficacy.