Over a person's lifetime they are likely to be prescribed more than 14,000 pills. Antibiotics, cholesterol lowering tablets, anti-depressants, painkillers, even tablets to extend youth and improve performance in bed. These drugs perform minor miracles day after day, but how much is really known about them? Drug discovery often owes as much to serendipity as to science, and that means much is learnt about how medicines work, or even what they do, when they're taken. By investigating some of the most popular pills people pop, Horizon asks, how much can they be trusted to do what they are supposed to?

COVID-19 is far from the first pandemic to wreak havoc in the world. A long line of infectious diseases have devastated and in some cases destroyed entire societies. Almost all of them started in animals and made the jump to humans. The Black Death spread across Europe and Asia in the 14th century leaving millions dead in its wake. Between the 15th and 18th centuries, European colonists brought smallpox to the Americas, the Pacific region and to Australia. In Europe, the 17th century saw a series of major epidemics. And at the end of the First World War, more people died of the Spanish flu than on the battlefield.
This documentary examines the causes of these epidemics - whether it be lack of hygiene, interaction with animals, overcrowding, or the growth of cities - and how people travelling helped to spread disease and promote pandemics. It also sheds a light on the impact these infectious diseases have had on politics and societal change. Over the centuries, scientists managed to develop treatments and medicines to help control or even eradicate infectious diseases. Virologists are facing that task again with the coronavirus, as the world frantically searches for ways to overcome a pandemic which threatens our modern way of life.

Adam Rutherford meets a new creature created by American scientists, the spider-goat. It is part goat, part spider, and its milk can be used to create artificial spider's web. It is part of a new field of research, synthetic biology, with a radical aim: to break down nature into spare parts so that we can rebuild it however we please. This technology is already being used to make bio-diesel to power cars. Other researchers are looking at how we might, one day, control human emotions by sending 'biological machines' into our brains.

The film explores the revolutionary gene-editing tech now giving humankind the freedom to redraw the blueprint of biological life itself. We investigate not only the tremendous potential the technology holds, whether in the fight to eliminate diseases or in transforming agriculture to adapt to unprecedented climate extremes, but also probe the inherent risks involved and the potential for widespread abuse, dangers that could take our future down a very dark, dystopian path.

In a world where the pursuit of health pushes us towards organic aisles and fresh produce, this film uncovers a chilling revelation: the very foods promoted for wellness might be our greatest peril. As we navigate grocery store aisles, seemingly benign items like romaine lettuce, cut fruit, and even infant formula hide tales of contamination and legal battles. This gripping exposé dives deep into the unsettling truth about our food, revealing risks where we least expect them.
With every bite, we make choices about our health. But what if those choices, even the most well-intentioned ones, are not as safe as we believe? Poisoned: The Dirty Truth About Your Food challenges our perceptions and urges viewers to question: In the modern food landscape, is anything truly safe? The film is a truly call to action for the officials who have the power to mitigate the danger caused by foodborne pathogens that kill thousands of people every year.

Director Chris Bell turns his camera on the abuse of prescription drugs and, ultimately, himself. After witnessing friends and relatives face tragedy as they become addicted to prescription drugs, Bell sets out to explore the goals of pharmaceutical companies and doctors in this ever-growing market, and asks how they are any different from back-alley drug-pushers. His journey leads to experts on the nature of addiction in our culture, as well as to pharmaceutical whistleblowers that testify to the solely dollar-driven aims of pharmaceutical companies.