A documentary-horror film exploring the phenomenon of 'Sleep Paralysis' through the eyes of eight very different people. These people often find themselves trapped between the sleeping and waking worlds, totally unable to move but aware of their surroundings while being subject to frequently disturbing sights and sounds. A strange element to these visions is that despite the fact that they know nothing of one another, many see similar ghostly 'shadow men.' This is one of many reasons many people insist this is more than just a sleep disorder". This documentary digs deep into not only the particulars of these eight people's uncanny experiences, but it also explores their search to understand what they've gone through and how it's changed their lives. Directed by Rodney Ascher, he chose to focus on sleep paralysis as it had happened to him in the past. The film's crew initially began approaching participants via message groups, videos and a half dozen books that had been written.

Around the world, food allergies are surging to near-epidemic levels. Medicine is just beginning to understand why some people react to seemingly harmless foods. Scientists race to understand what's changed in our bodies, while farmers and chefs contend with new challenges.

Placebos come in all shapes and sizes, but they contain no active ingredient. They are the miracle pills that shouldn't really work at all. Now they are being shown to help treat pain, depression and even alleviate some of the symptoms of Parkinson's disease. It seems they're not acting alone. The placebo effect is intertwined with how is did the healthcare. Explores why they work, and how we could all benefit from the hidden power of the placebo.

A ground-breaking new trial at Imperial College London sees, for the first time ever under controlled conditions, a psychedelic drug tested head-to-head against a standard antidepressant as a treatment for depression. The film follows a pioneering team of scientists and psychotherapists as they compare the effects of psilocybin (the active ingredient of magic mushrooms) with an antidepressant on a small group of participants with clinical depression.
This is scientific research at its most cutting edge. With over seven million people being prescribed antidepressants each year in England alone, this drug trial is an important milestone in understanding a completely different treatment for depression. How do psychedelic drugs measure up against the industry-standard antidepressants that have been popular since the 1990s? The empirical results of the trial are explored alongside the participants’ powerful lived experience.

Gaby Roslin and Amir Khan present a program in which they apply the latest science to some of the worst sleepers. They include an extreme snorer, a man who suffers from night terrors, a woman who has restless leg syndrome, and a man with chronic insomnia for 20 years.
The film also shows a sleep deprivation experiment to test for risky behaviour, pain resistance and emotional control. When the subjects reach the final hours of the challenge, the experiment begins to take its toll as the participants' emotions go into overdrive, with one threatening to quit altogether.

Professor Marcus du Sautoy goes in search of answers to one of science's greatest mysteries: how do we know who we are? While the thoughts that make us feel as though we know ourselves are easy to experience, they are notoriously difficult to explain. He has his mind scrambled by a cutting-edge experiment in anaesthesia. After, Marcus is given an out-of-body experience in a bid to locate his true self.