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An informative and ambitious journey exploring how the evolution of scientific understanding is intimately interwoven with society's historical path. The Story Of Science tells the forces that came together to create scientific knowledge; the practical business of making instruments and machines; the great forces of history – revolutions, voyages of discovery and artistic movements – and the dogged determination of scientists and experimenters. This is the story of how scientific ideas shaped the modern world and how science made history. Michael Mosley begins the first episode with the story of one of the great upheavals in human history - how we came to understand that our planet was not at the centre of everything in the cosmos, but just one of billions of bodies in a vast and expanding universe. He reveals the critical role of medieval astrologers in changing our view of the heavens, and the surprising connections to the upheavals of the Renaissance, the growth of coffee shops and Californian oil and railway barons. Michael shows how important the practical skills of craftsmen have been to this story and finds out how Galileo made his telescope to peer at the heavens and by doing so helped change our view of the universe forever.

There is a strange and mysterious world that surrounds us, a world largely hidden from our senses. The quest to explain the true nature of reality is one of the great scientific detective stories. Clues have been pieced together from deep within the atom, from the event horizon of black holes, and from the far reaches of the cosmos. It may be that we are part of a cosmic hologram, projected from the edge of the universe. Or that we exist in an infinity of parallel worlds. Your reality may never look quite the same again.

Horizon investigates the idea that the best way to lose weight successfully is a personalised approach, diets tailored to our individual biology and psychology. In a groundbreaking experiment, Dr Chris van Tulleken and Tanya Byron join a team of experts to put 75 overweight volunteers on diets designed to tackle the specific reasons why they eat too much. The volunteers are put through a series of tests at a residential clinic to understand how their genes, hormones and psychology influence their eating behaviour. They are then put on the diets the experts believe are best suited to them. Can science succeed where other diets have failed?

It is time to see if personalised dieting will work in normal life. The volunteers have been given one of three diets to follow - based on their genes, their hormones and their psychology. But now they are back at home, trying to stick to their personalised diets with all the stresses and temptations of real life. Dr Chris van Tulleken and Professor Tanya Byron discover how our genetic makeup can make temptation difficult to resist, how understanding the brain reveals what makes us comfort eat and what science can tell us about why we make disastrous food choices.

So far the volunteers have successfully been losing lost weight, but now the honeymoon period is over. It is the final two months of the diet, and their minds and bodies are fighting back. Dr Chris van Tulleken and Professor Tanya Byron find out if the new personalised diets will help them stay on course, and the experts reveal the scientific secrets to permanent dieting success.

The story of how the secret of life has been examined through the prism of the most complex organism known - the human body. It begins with attempts to save the lives of gladiators in Ancient Rome, unfolds with the macabre work and near-perfect drawings of Leonardo in the Renaissance, through the idea of the 'life force' of electricity, to the microscopic world of the cell. It reveals how a moral crisis unleashed by work on the nuclear bomb helped trigger a great breakthrough in biology - understanding the structure and workings of DNA.