Our lifespan is increasing by 2.5 years every decade - and a third of all babies born today can expect to live to 100. But living longer can come at a cost. Old age itself brings with it a range of debilitating illnesses, many of which are the result of accumulating damage during our lifetime. Three diseases in particular have become the main killers in the developed world - cancer, heart disease and dementia. But a revolution in bio-medicine is now offering new hope for the treatment of these ailments, and the potential to extend our lives still further. Methods such as gene editing and stem cell therapies are transforming the way medicine can conquer disease today. "How to Live Longer" counts with the guide of the Nobel laureate Sir Paul Nurse, for whom the big question isn't just what science can do to fix our bodies and extend our lives, but whether it's right to use all the tools and techniques available.

Trailblazing scientists are making ground-breaking discoveries in the rapidly evolving world of genetic engineering. Technologies like CRISPR are making it possible to quickly and cheaply change the DNA of all living things, including humans. Today, genes can be edited almost as easily as words on a computer screen. This new ability to alter our DNA holds the promise of curing disease , saving threatened species, solving the problem of world hunger and maybe even obtaining human perfection. But will the promise be fulfilled and at what cost?
The ability to gain control of our DNA is ground-breaking and revolutionary but there are varying opinions among scientists as to how the technology should be used responsibly. This documentary follows the science as it progresses at a breakneck speed.