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Professor Jim Al-Khalili investigates the most accurate and yet perplexing scientific theory ever - quantum physics. At the beginning of the 20th century scientists were led into the hidden workings of matter, into the sub-atomic building blocks of the world around us. They discovered phenomena unlike any encountered before - a realm where things can be in many places at once, where chance and probability call the shots and where reality appears to only truly exist when we observe it. Albert Einstein hated the idea that nature, at its most fundamental level, is governed by chance. Jim reveals how, in the 1930s, Einstein thought he'd found a fatal flaw in quantum physics because it implies that sub-atomic particles can communicate faster than light in defiance of the theory of relativity. In the 1960s the scientist John Bell showed there was a way to test if Einstein was right and quantum mechanics was actually mistaken. Jim repeats this critical experiment - with shocking results.

Professor of physics Jim Al-Khalili investigates the most accurate and yet perplexing scientific theory ever - quantum physics, the perplexing theory of sub-atomic particles. Turning his attention to the world of nature, can quantum mechanics explain the greatest mysteries in biology? The European robin navigates using one of the most bizarre effects in physics - quantum entanglement, a process which seems to defy common sense. Jim finds that even the most personal of human experiences - our sense of smell - is touched by ethereal quantum vibrations. According to new experiments it seems that our quantum noses are listening to smells. Jim discovers that the most famous law of quantum physics - the uncertainty principle - is obeyed by plants and trees as they capture sunlight during the vital process of photosynthesis. Jim wonders if the strange laws of the sub-atomic world, which allow objects to tunnel through impassable barriers in defiance of common sense, could effect the mechanism by which living species evolve?

The second part, Nothing, explores science at the very limits of human perception, where we now understand the deepest mysteries of the universe lie. Professor Jim Al-Khalili sets out to answer one very simple question - what is nothing? His journey ends with perhaps the most profound insight about reality that humanity has ever made. Everything came from nothing. The quantum world of the super small shaped the vast universe we inhabit today, and Jim can prove it.

Mark Oliver Everett, singer of the band EELS, on his quest to get to know his later father, quantum physicist Hugh Everett III, who invented the Many Worlds theory. The film follows Mark on his journey across America, where he meets old friends and colleagues of his father. Hugh died of a heart attack in his home in 1982, where his body was found by 19-year-old Mark. Even though they had lived in the same house, the two of them were alienated. Only by entering the paradoxical world of quantum mechanics can Mark hope to understand why he was such a stranger to his own father.

Stephen Hawking is the most famous scientist on the planet. But behind the public face lies an argument that has been raging for almost 30 years. Has he been wrong for the last 30 years? Hawking shot to fame in the world of physics when he provided a mathematical proof for the Big Bang theory. This theory showed that the entire universe exploded from a singularity, an infinitely small point with infinite density and infinite gravity. Hawking was able to come to his proof using mathematical techniques that had been developed by Roger Penrose. These techniques were however developed to deal not with the beginning of the Universe but with black holes". Science had long predicted that if a sufficiently large star collapsed at the end of its life, all the matter left in the star would be crushed into an infinitely small point with infinite gravity and infinite density – a singularity. Hawking realised that the Universe was, in effect, a black hole in reverse. Instead of matter being crushed into a singularity, the Universe began when a singularity expanded to form everything we see around us today, from stars to planets to people. Hawking realised that to come to a complete understanding of the Universe he would have to unravel the mysteries of the black hole and its paradoxes

Richard Dawkins examines the growing suspicion the public has for science-based medicine, despite its track record of successes like the germ theory of disease, vaccines, antibiotics and increased lifespan. He notes a fifth of British children are currently not immunised against measles, mumps and rubella, attributing it to fears arising from a highly controversial report linking the vaccine with autism. Dawkins criticizes the growing field of alternative medicine which does not pass the same objective and statistical rigour as scientifically derived treatments using controlled double-blind studies. Without verifiable evidence, alternative therapies must rely on biased anecdotes and word of mouth to perpetuate. Dawkins observes these treatments have fanciful rationales and rituals behind them, with many alternative treatments employing pseudoscientific jargon such as "energy", "vibration" or "quantum theory" to give themselves greater credence to patients.