An epic documentary film in which nine scientists will meet in a chain of encounters to uncover unexpected answers to some of humanity's biggest questions. How did life begin? What is time? What is consciousness? How much do we really know? By introducing researchers from diverse backgrounds for the first time, then dropping them into new, immersive field work they previously hadn't tackled, the film reveals the true potential of interdisciplinary collaboration, pushing the boundaries of how science storytelling is approached.
What emerges is a deeply human trip to the foundations of discovery and a powerful reminder that the unanswered questions are the most crucial ones to pose. The Most Unknown is an ambitious look at a side of science.

Memory is the glue that binds our mental lives. Without it, we’d be prisoners of the present, unable to use the lessons of the past to change our future. From our first kiss to where we put our keys, memory represents who we are and how we learn and navigate the world. But how does it work? Neuroscientists using cutting-edge techniques are exploring the precise molecular mechanisms of memory". By studying a range of individuals ranging —from an 11-year-old whiz-kid who remembers every detail of his life to a woman who had memories implanted— scientists have uncovered a provocative idea. For much of human history, memory has been seen as a tape recorder that faithfully registers information and replays intact. But now, researchers are discovering that memory is far more malleable, always being written and rewritten, not just by us but by others. We are discovering the precise mechanisms that can explain and even control our memories. The question is— are we ready?

After several rogue traders stories made the headlines these last years, revealing the human factor behind the global economy, neuroscientists have started to scrutinize traders' brain and stress management. What stimulates and motivates them? How can their brain cope with such a high level of stress and competition? This film investigates further into Neuroeconomics, showing how traders are being governed by unconscious psychological and biological processes which can trigger borderline behaviours and have disastrous financial consequences on the financial markets.

The human brain is the most complex object we’ve discovered in the universe, and every day much of its neural circuitry is taken up with the tens of thousands of decisions we need to make. ‘How do I decide?’ is a journey through the unseen world of decisions, and how they get made. Decisión-making is what allows us to navigate a course through life. Discover how important emotions are in making decissions and, as we learn more about our own brains, we can break away from slavery to our impulses. Neuroscience shows that you're made up of multiple competing drives and by understanding how choices battle it out in the brain, we can learn how to make better decisions.

Mind reading might sound like pseudoscientific, but its scientific counterpart, thought identification, is very much a real thing. It's based in neuroimaging and machine learning, and what's really cool is that experiments in mind reading aren't just about spying on what someone is thinking. They're about figuring out what thoughts are even made of.
When you think of something, what does that mental picture actually look like? What resolution is it in? How high fidelity is a memory, and how do they change over time? In this episode, we are going to look at how reading people's minds can help us answer these questions.

In ‘Who will we be?’ Dr. David Eagleman journeys into the future, and asks what’s next for the human brain, and for our species. We stand at a major turning point, one where we might take control of our own development. We face a future of uncharted possibilities in which our relationship with our own body, our relationship with the world, the very basic nature of who we are is set to be transformed. For thousands of generations, humans have lived the same life cycle over and over. We are born, we control a fragile body, we experience a limited reality, and we die. But science and technology are giving us tools to transcend that evolutionary story. Our brains don't have to remain as we have inherited them. We are capable of extending our reality, of inhabiting new bodies, and possibly shedding our physical forms altogether. And we are discovering the tools to shape our own destiny. Who we become is up to us.