Modern headlines are claiming mindfulness may cure anxiety, depression, and a whole host of other health problems. How can this simple practice of watching your own breath change the way your brain works? And can that change your life? The fourth episode of the series looks at the power of mindfulness and meditation. It examines different kinds on meditation (transcendental, dynamic, and religious) and notes that they are different from mindfulness meditation (Satipatthana). Also it talks to neuroscientists who discuss what happens in the brain during meditation.

This episodes the nature of the cosmos on the micro and atomic scales, using the Ship of the Imagination to explore these realms. Tyson describes some of the micro-organism that live within a dew drop, demonstrating parameciums and tardigrades. He proceeds to discuss how plants use photosynthesis via their chloroplasts to convert sunlight into chemical reactions that convert carbon dioxide and water into oxygen and energy-rich sugars. Tyson then discusses the nature of molecules and atoms and how they relate to the evolution of species. He uses the example set forth by Charles Darwin postulating the existence of the long-tongued Morgan's sphinx moth based on the nature of the comet orchid with pollen far within the flower. He further demonstrates that scents from flowers are used to trigger olfactory centers in the brain, stimulating the mind to threats as to aid in the survival of the species. Tyson narrates how Greek philosophers Thales and Democritus postulated that all matter was made up of combinations of atoms in a large number of configurations, and describes how carbon forms the basic building block for life on earth due to its unique chemical nature. Tyson explains on the basic atomic structure of protons, neutrons, and electrons, and the nature of nuclear fusion that occurs in most stars. He then discusses the existence of neutrinos that are created by these nuclear processes in stars, and that detecting such sub-atomic particles which normally pass through matter require subterranean facilities like the Super-Kamiokande that were used to detect neutrinos from the supernova SN 1987A in the Large Magellanic Cloud before light from the explosion were observed due to their ability to pass through matter of the dying sun. Tyson compares how neutrinos were postulated by Wolfgang Pauli to account for the conservation of energy from nuclear reactions in the same manner as Darwin's postulate on the long-tongued moth. Tyson concludes by noting that there are neutrinos from the Big Bang still existing in the universe but due to the nature of light, there is a "wall of infinity" that cannot be observed beyond.

Neuroscientist David Eagleman explores the human brain in an epic series that reveals the ultimate story of us, why we feel and think the things we do. This ambitious project blends science with innovative visual effects and compelling personal stories, and addresses some big questions. By understanding the human brain, we can come close to understanding humanity". In this episode, Dr. Eagleman takes viewers on an extraordinary journey that explores how the brain, locked in silence and darkness without direct access to the world, conjures up the rich and beautiful world we all take for granted.

Why do we sleep? And what does sleep have to do with memory, trauma, and our emotions? From fruit flies to whales, virtually every animal sleeps. But why? Why do we need to spend nearly a third of our lives in such a defenseless state? Scientists are peering more deeply into the sleeping brain than ever before, discovering just how powerful sleep can be, playing a role in everything from memory retention and emotional regulation to removing waste from our brains. So why are we getting so little of it?

Not an animal, nor a plant, nor fungi, the blob is one giant single cell whose amazing capacities are leading pioneer scientists to a very new world – that of brainless intelligence. More commonly known as slime mould, this extraordinary one-billion-year-old organism challenges our understanding in many different fields.
This fascinating documentary follows top experts from Europe, Japan and the US on a scientific investigation into this most surprising organism.

An epic documentary film in which nine scientists will meet in a chain of encounters to uncover unexpected answers to some of humanity's biggest questions. How did life begin? What is time? What is consciousness? How much do we really know? By introducing researchers from diverse backgrounds for the first time, then dropping them into new, immersive field work they previously hadn't tackled, the film reveals the true potential of interdisciplinary collaboration, pushing the boundaries of how science storytelling is approached.
What emerges is a deeply human trip to the foundations of discovery and a powerful reminder that the unanswered questions are the most crucial ones to pose. The Most Unknown is an ambitious look at a side of science.