More than a decade ago, scientists announced that they had produced the first draft of the human genome, the 3.6 billion letters of our genetic code. It was seen as one of the greatest scientific achievements of our age, a breakthrough that would usher in a new age of medicine. Find out how close we are to developing the life-changing treatments that were hoped for". Follow three people, each with a genetic disease, as they go behind the scenes at some of Britain's leading research labs to find out what the sequencing of the human genome has done for them - and the hope this remarkable project offers all of us.

This episode covers the nature of how life may have developed on Earth and the possibility of life on other planets. Tyson begins by explaining how the human development of writing systems enabled the transfer of information through generations, describing how Princess Enheduanna ca. 2280 BCE would be one of the first to sign her name to her works, and how Gilgamesh collected stories, including that of Utnapishtim documenting a great flood comparable to the story of Noah's Ark. Tyson explains how DNA similarly records information to propagate life, and postulates theories of how DNA originated on Earth, including evolution from a shallow tide pool, or from the ejecta of meteor collisions from other planets. In the latter case, Tyson explains how comparing the composition of the Nakhla meteorite in 1911 to results collected by the Viking program demonstrated that material from Mars could transit to Earth, and the ability of some microbes to survive the harsh conditions of space. With the motions of solar systems through the galaxy over billions of years, life could conceivably propagate from planet to planet in the same manner. Tyson then moves on to consider if life on other planets could exist. He explains how Project Diana performed in the 1960s showed that radio waves are able to travel in space, and that all of humanity's broadcast signals continue to radiate into space from our planet. Tyson notes that projects have since looked for similar signals potentially emanating from other solar systems. Tyson then explains that the development and lifespan of extraterrestrial civilizations must be considered for such detection to be realized. He notes that civilizations can be wiped out by cosmic events like supernovae, natural disasters such as the Toba disaster, or even self-destruct through war or other means, making probability estimates difficult. Tyson describes how elliptical galaxies, in which some of the oldest red dwarf stars exist, would offer the best chance of finding established civilizations. Tyson concludes that human intelligence properly applied should allow our species to avoid such disasters and enable us to migrate beyond the Earth before the Sun's eventual transformation into a red giant.

The film explores how artificial intelligence (AI) is catching up to us in ways once thought to be uniquely human: empathy, emotional intelligence and creativity. AI has the potential to reshape every aspect of our world – but most of us are unaware of what looms on the horizon. This documentary shows viewers what they need to know about a field that is advancing at a dizzying pace, often away from the public eye. Have AI the power to disconnect us from fellow humans? What does it mean when AI makes art? Can really AI interpret and understand human emotions? How is it possible that AI creates sophisticated neural networks that mimic the human brain?
The documentary includes interviews with global leaders, commentators and innovators from the AI field, including Geoff Hinton, Yoshua Bengio, Ray Kurzweil and Douglas Coupland, who highlight some of the innovative and cutting-edge AI technologies that are changing our world.

It's a timeless classic of children's literature and the third most-quoted book in English after the Bible and Shakespeare. But what lies behind the extraordinary appeal of Alice's Adventures in Wonderland to generations of adults and children alike? To mark the 150th anniversary of its publication, this documentary explores the life and imagination of the man who wrote it, the Reverend Charles Dodgson, better known as Lewis Carroll." Broadcaster and journalist Martha Kearney delves into the biographies of both Carroll himself and of the young girl, Alice Liddell, who inspired his most famous creation. Kearney's lifelong passion for Carroll's work began as a young girl, when she starred as Carroll's heroine Alice in her local village play. She discusses the book with a range of experts, biographers and distinguished cultural figures - from the actor Richard E Grant to children's author Philip Pullman - and explores with them the mystery of how a retiring, buttoned-up and meticulous mathematics don, who spent almost his entire life within the cloistered confines of Christ Church Oxford, was able to capture the world of childhood in such a captivating way

Every year, over a thousand climbers try to reach the summit of Mount Everest, with the annual record for successful attempts currently standing at 633. But of that number, nearly half were Sherpas - the mountain's unsung heroes. Yet the Sherpa community has remained secretive about their nation, culture and experiences living in the shadow of the world's highest mountain. Now, for the first time, they open the door into their world. Without the expertise of the Sherpas, only the hardiest and most skilful climbers would succeed. Every day they risk their lives for the safety of others, yet they seek neither glory nor reward, preferring to stay in the background. Following the stories of four such Sherpas - Phurba, Ngima, Ngima Tenji and Gelu - this film reveals the reality of their daily lives, not just up the mountain, but with their families after they return home.

Mysterious lights shine out from the edge of space, brighter than a trillion suns. They had to be the brightest objects we've ever seen in the universe, putting out amounts of energy that we couldn't possibly explain. So powerful, they can incinerate planets and rip stars to pieces. These are among the most mysterious and most energetic phenomenon in the universe. They can destroy galaxies, but may also be the key to their survival. These objects are a hotbed of all kinds of crazy physics. These celestial powerhouses are called quasars, and we may owe them our very existence.