Questions are raised about the search for intelligent life beyond the Earth, with UFOs and other close encounters refuted in favor of communications through SETI and radio telescope such as the Arecibo Observatory. The probability of technically advanced civilizations existing elsewhere in the Milky Way is interpreted using the Drake equation and a future hypothetical Encyclopedia Galactica is discussed as a repository of information about other worlds in the galaxy. The Cosmos Update notes that there have been fewer sightings of UFOs and more stories of abductions, while mentioning the META scanning the skies for signals.

This series takes viewers on a journey to the frontiers of science, where researchers are tackling some of the biggest questions about life and the cosmos. The universe is hiding something. In fact, it is hiding a lot. Everything we experience on Earth, the stars and galaxies we see in the cosmos—all the 'normal' matter and energy that we understand—make up only 5% of the known universe. The other 95% is made up of two mysterious components: 'dark matter' and 'dark energy.' We can’t see them, but we know they’re there. And what’s more —these two shadowy ingredients are locked in an epic battle to control the very fate of the universe.
Now, scientists are trying to shed light on the so-called 'dark sector' as the latest generation of detectors rev up, and powerful telescopes peer deeper into space than ever before to observe how it behaves. Will the discoveries help reveal how galaxies formed? In the series finale, Nova Wonders journeys to the stars and back to investigate what we know —and don’t know. Find out how scientists are discovering new secrets about the history of the universe, and why they’re predicting a shocking future.

Sagan discusses comets and asteroids as planetary impactors, giving recent examples of the Tunguska event and a lunar impact described by Canterbury monks in 1178. It moves to a description of the environment of Venus, from the previous fantastic theories of people such as Immanuel Velikovsky to the information gained by the Venera landers and its implications for Earth's greenhouse effect. The Cosmos Update highlights the connection to global warming.

Stephen Hawking, the world's most famous living scientist explores the greatest mysteries of the cosmos. In three landmark instalments he reveals the wonders of the universe as never seen before. Definitive, provocative, surprising, and beautiful, Into the Universe with Stephen Hawking is a fascinating look through the mind's eye of one of the finest brains on the planet. In 'Aliens' Hawking considers one of the most important mysteries facing humankind - the possibility of alien, intelligent life. He leads us on a journey rendered in eye-popping detail, from the moons of Jupiter to a galaxy maybe not so far, far away. We will meet possible aliens and wonder at their form, we will delve into the very principles of what it is to call something alive, and we will calculate the likelihood of 'contact' being made.

The simple act of making an apple pie is extrapolated into the atoms and subatomic particles (electrons, protons, and neutrons) necessary. Many of the ingredients necessary are formed of chemical elements formed in the life and deaths of stars (such as our own Sun), resulting in massive red giants and supernovae or collapsing into white dwarfs, neutron stars, pulsars, and even black holes. These produce all sorts of phenomena, such as radioactivity, cosmic rays, and even the curving of spacetime by gravity. Cosmos Update mentions the supernova SN 1987A and neutrino astronomy.

Sagan reflects on the future of humanity and the question of 'who speaks for Earth?' when meeting extraterrestrials. He discusses the very different meetings of the Tlingit people and explorer Jean-François de La Perouse with the destruction of the Aztecs by Spanish conquistadors, the looming threat of nuclear warfare, and the threats shown by destruction of the Library of Alexandria and the murder of Hypatia. The episode ends with an overview of the beginning of the universe, the evolution of life, and the accomplishments of humanity and makes a plea to mankind to cherish life and continue its journey in the cosmos. The Cosmos Update notes the preliminary reconnaissance of planets with spacecraft, the fall of the Berlin Wall and the end of apartheid in South Africa, and measures towards the reduction of nuclear weapons.