Angela Rippon and Dr Chris van Tulleken travel the world in search of the latest science that could help us all stay young and healthy for longer. They investigate the best ways to help both our bodies and brains age better. Up first is the body, and Angela travels to Germany to join a groundbreaking study which reveals the exercise that holds off ageing the most. Chris visits America to find out about the unexpected diet that can add years to our lives. And in Ecuador we meet a seventeen-year-old who looks like a child to discover how scientists hope he may hold the key to preventing the diseases of ageing.

Is God worshipped in other worlds, across the cosmos? How might alien deities differ from our own? The answer may lie buried on Earth. Animal behaviorists are testing elephants and finding them capable of having spiritual thoughts. Artificial intelligence researchers are building enlightened robots that contemplate the divine. Meanwhile, cosmologists are looking for universal equations that could replace God. Have advanced aliens discovered everything there is to know about the universe? Or are they looking to a higher power for answers?

A portrait of Dr. Anthony Fauci, the public servant, scientist, physician, husband and father whose career spans seven presidents and is bookended by two pandemics: HIV/AIDS, which shaped him, and of course, COVID-19; the latter bringing him countless TV appearances in American homes on an almost daily basis over the course of nearly two years.

Marcus Du Sautoy wants to find out how close we are to creating machines that can think like us: robots or computers that have artificial intelligence. His journey takes him to a strange and bizarre world where AI is now taking shape. Marcus meets two robots who are developing their own private language, and attempts to communicate to them. He discovers how a super computer beat humans at one of the toughest quiz shows on the planet, Jeopardy". And finds out if machines can have creativity and intuition like us. Marcus is worried that if machines can think like us, then he will be out of business. But his conclusion is that AI machines may surprise us with their own distinct way of thinking.

Professor Simon Schaffer presents the amazing and untold story of automata - extraordinary clockwork machines designed hundreds of years ago to mimic and recreate life. The film brings the past to life in vivid detail as we see how and why these masterpieces were built. Travelling around Europe, Simon uncovers the history of these machines and shows us some of the most spectacular examples, from an entire working automaton city to a small boy who can be programmed to write and even a device that can play chess". All the machines Simon visits show a level of technical sophistication and ambition that still amazes today. As well as the automata, Simon explains in great detail the world in which they were made - the hardship of the workers who built them, their role in global trade and the industrial revolution and the eccentric designers who dreamt them up. Finally, Simon reveals that to us that these long-forgotten marriages of art and engineering are actually the ancestors of many of our most loved modern technologies, from recorded music to the cinema and much of the digital world.

Sagan discusses the story of the Heike crab and artificial selection of crabs resembling samurai warriors, as an opening into a larger discussion of evolution through natural selection (and the pitfalls of intelligent design). Among the topics are the development of life on the Cosmic Calendar and the Cambrian explosion; the function of DNA in growth; genetic replication, repairs, and mutation; the common biochemistry of terrestrial organisms; the creation of the molecules of life in the Miller-Urey experiment; and speculation on alien life (such as life in Jupiter's clouds). In the Cosmos Update ten years later, Sagan remarks on RNA also controlling chemical reactions and reproducing itself and the different roles of comets (potentially carrying organic molecules or causing the Cretaceous–Paleogene extinction event).