Where will loved ones spend their last days? Who will be in the room? What feelings and secrets need to be shared with family before it is too late? Acclaimed filmmakers Rob Epstein and Jeffrey Friedman probe these questions and more in the context of two San Francisco Bay Area medical facilities on the forefront of creating new paradigms for end of life decisions with grace.
Filmed and edited in intimate vérité style, 'End Game' follows visionary medical practitioners who are working on the cutting edge of life and death and are dedicated to changing our thinking about both.

The Spirit Molecule investigates dimethyltryptamine (DMT), a naturally occurring psychoactive compound, which exists in humans, and potentially every living organism. Utilizing Dr. Rick Strassman's government-sanctioned, human DMT research as the documentary's backbone, the study's potential impact and its inconceivable revelations emerge. A closer examination of DMT's effects through two traditionally opposed concepts, science and spirituality, The Spirit Molecule unravels the connections between cutting-edge neuroscience, quantum mechanics and human spirituality.
The Spirit Molecule, a simple molecule with enormous implications. The subtle combination of science, spirituality, and philosophy results in an abundance of incredible ideas and theories that could alter the way we understand the nature of reality and our relationship to it.

The documentary explores the controversial use of marijuana and the evolution of mainstream society. From a dangerous narcotic, listed as a Schedule 1 Drug substance since the 1970s, to the rush to decriminalize it today. What has changed and why? What will the cannabis industry look like in five years? Will it retain its integrity as a homegrown industry or be co-opted by Big Business? Experts, growers, celebrities and politicians weigh in on the future of Cannabusiness.

A ground-breaking new trial at Imperial College London sees, for the first time ever under controlled conditions, a psychedelic drug tested head-to-head against a standard antidepressant as a treatment for depression. The film follows a pioneering team of scientists and psychotherapists as they compare the effects of psilocybin (the active ingredient of magic mushrooms) with an antidepressant on a small group of participants with clinical depression.
This is scientific research at its most cutting edge. With over seven million people being prescribed antidepressants each year in England alone, this drug trial is an important milestone in understanding a completely different treatment for depression. How do psychedelic drugs measure up against the industry-standard antidepressants that have been popular since the 1990s? The empirical results of the trial are explored alongside the participants’ powerful lived experience.

Psychopaths have long captured the public imagination. Painted as charismatic, violent predators lacking in all empathy, they provide intrigue and horror in equal measure. But what precisely is a psychopath? What is it that drives them to cause harm, even kill? And can they ever be cured? The film also features a series of candid interviews with prison inmates who not only describe their crimes but why they think they committed them.
'What Makes a Psychopath?' explores not only how each individual's crimes were shaped by their own life experiences, but also gives an insight into how these people think and behave. Working with the world's experts in the field, the film sheds light on the biological, psychological and environmental influences that shape a psychopath. And it looks to the future, with ground-breaking research that suggests a lifetime of incarceration is not the only option to manage violent and dangerous psychopaths.

Hear firsthand from individuals struggling with addiction and follow the cutting-edge work of doctors and scientists as they investigate why addiction is not a moral failing, but a chronic, treatable medical condition. Easy access to drugs like heroin, fentanyl, and even prescription medications like OxyContin has fueled an epidemic of addiction - the deadliest in US history. Now, science is revealing how addiction affects the brain, and top experts are gathering evidence about how we should address our drug problem, from embracing evidence-based treatments, to rethinking public policies.