Dr Jago Cooper reveals the history of some of South America's ancient civilisations. He begins with an epic journey into the remote Peruvian Andes in search of the mysterious Chachapoya people. Once numbering half a million, they were known as the 'People of the Clouds'. Dr Cooper reveals how they developed sophisticated methods of recording stories, traded in exotic goods found hundreds of miles from their territory, and had funeral traditions that challenge assumptions about ancient human behaviour. His search for evidence takes him to astonishing cliff tombs untouched for 500 years and one of the most spectacular fortresses in South America, where the fate of the Chachapoya is revealed.

We are in the grip of an allergy epidemic. 50 years ago one in 30 were affected, but in Britain today it is closer to one in three. Why this should be is one of modern medicine's greatest puzzles. In search of answers, Horizon travels round the globe, from the remotest inhabited island to the polluted centres of California and the UK. We meet sufferers and the scientists who have dedicated their lives trying to answer the mystery of why we are becoming allergic to our world.

Let's go behind the scenes at NASA to discover how it is preparing for its most ambitious and daring mission: to land men - and possibly women - on the surface of Mars. It's over 40 years since Neil Armstrong made the first human footprint on the moon. But getting to the red planet would involve a journey of at least three years. Meet the scientists and engineers who are designing new rockets, new space suits and finding ways to help astronauts survive the perils of this long voyage. And it turns out that having the 'right stuff' for a mission to mars might not be quite what you expect.

Dr. Thomas Asbridge explains how in the thirteenth century, after almost two hundred years of Holy Wars, the titanic conflict between Christianity and Islam, known to history as The Crusades, reached a decisive and shocking conclusion – a chapter that despite its drama has been virtually forgotten. He explains how, in the end, the fate of the Holy Land was decided not on the hallowed ground of Jerusalem, but in Egypt; and how the ultimate outcome of the Crusades was dictated not by Christians, but by the Mongol successors to Genghis Khan, and by a Muslim slave – a fearsome warrior whose story is now all but lost to western history.

Serial killer Dennis Nilsen narrates his life and horrific crimes via a series of chilling audiotapes recorded from his jail cell. Set against the backdrop of 1980s Britain, when mass unemployment drew young men to London in search of their fortunes, only to find themselves destitute and easy prey, and weaving together interviews from police, journalists, survivors, bereaved families, and - for the first time the killer's own voice, this feature length documentary explores how Nilsen was able to get away with multiple murders and attacks, unchallenged, for five years.

In episode two, Professor Brian Cox is off to India, where he assesses arguably the first evidence of rational thought in literature, the poetry of the Vedic monks. They pondered mankind's origins, realising there must have been a day with no yesterday - a day of creation - prompting the age-old question of where did the universe come from? Brian marvels that the universe seems to follow a set of rules, the laws of physics, allowing space to be considered on the grandest scale, travelling to the most distant, farthest reaches of the cosmos just by using our minds. Brian also visits Japan, and offers viewers the idea that man lives in just one of an infinite number of universes that are being made all the time.