From the Philippines to the US, Madagascar and Mexico, Professor Brian Cox explores the globe to reveal how a few fundamental laws of science gave birth to the most complex and unique feature of the universe - life. In the first episode, Brian journeys to the volcanic landscapes of South-East Asia, seeking to understand how life first began and how that spark has endured to this day.

Is mankind alone, or are there aliens out there, either waiting to be discovered, or on their way to find Earth? Professor Brian Cox spends this episode asking such questions, and what he discovers may raise a few eyebrows. He begins by exploring the human race's efforts to find neighbours in outer space, including the launch of two golden discs containing a greeting from Earth in the 1970s; they are still travelling and are now the most distant man-made objects from the planet. Brian also meets members of the Search for Extra-Terrestrial Intelligence, who have been monitoring radio signals for 50 years without success, before discussing the ingredients needed to make an intelligent civilisation with astrophysicist Dr Frank Drake.

Professor Brian Cox fulfils a childhood dream by going behind the scenes at Nasa’s Jet Propulsion Laboratory (JPL), mission control for Mars 2020 – one of the most ambitious missions ever launched that may finally reveal if life ever existed on the red planet.
In 1980, a young Brian Cox wrote to JPL asking for photos from some of their missions to the planets. The pictures they sent him from Voyager and the Viking mission to Mars were a source of inspiration that set him on the path to becoming a physicist.
Now, over 40 years later, he has been granted privileged access to JPL, including key mission areas that are usually off-limits to film crews. Brian spends a week following the team who guide the Perseverance rover and the Ingenuity helicopter - the first powered aircraft ever sent to another planet - across the surface of Mars during a critical stage of the mission.
Perseverance’s goal is to search for signs of long extinct life on the surface of Mars in an area called Jezero Crater, which, 3.8 billion years ago, was filled by a vast lake. If it finds evidence of that life, it could change everything we know about life in the universe - and even transform our understanding of our own origins.

In episode two, Professor Brian Cox is off to India, where he assesses arguably the first evidence of rational thought in literature, the poetry of the Vedic monks. They pondered mankind's origins, realising there must have been a day with no yesterday - a day of creation - prompting the age-old question of where did the universe come from? Brian marvels that the universe seems to follow a set of rules, the laws of physics, allowing space to be considered on the grandest scale, travelling to the most distant, farthest reaches of the cosmos just by using our minds. Brian also visits Japan, and offers viewers the idea that man lives in just one of an infinite number of universes that are being made all the time.

Professor Brian Cox concludes his exploration of our place in the universe by asking what next for the ape that went to space. Our future is far from certain. In Florida, Brian joins the latest efforts to protect Earth from potential catastrophic events. He joins a team of Nasa astronauts who are training for a future mission to an asteroid - should we ever discover one coming our way - under 30 feet of water in a submerged laboratory that simulates space. It is just one example of how, for our long-term survival, space exploration may well be vital. It is a view shared by Apollo 16 astronaut Charlie Duke, who tells Brian what it was like to escape the confines of the planet. It is a dream that both Nasa and now commercial companies share as they race to get humans back into deep space.
But space travel, like every leap our civilisation has ever made, requires energy. Here too, scientists are hard at work attempting to safeguard our future. At the National Ignition Facility in California, Brian witnesses the world's most successful fusion experiment in action. He believes that if their mission succeeds, our civilisation will have unlocked a way to the stars that will not destroy the planet in the process. Brian concludes by returning to the top of the world in Svalbard, where he gains access to our civilisation's greatest treasure, locked away in a vault buried deep in the permafrost.

On a trip to the fortified Moroccan village of Ait-Ben-Haddou in the Atlas Mountains, Professor Brian Cox reveals how by watching the stars' motion across the night sky, it is quite natural for man to think he is at the centre of everything. That view was held for many ages, but innate human curiosity has eventually led to an understanding of mankind's true place in space and time, and an appreciation that Earth is not a focal point but a mere particle of rock in a possibly infinite expanse of space, 13.8 billion years from the beginning of the universe.