Ewan and Charley swap their e-Harley Davidsons for plane first and follow it up with a journey by ship to Panama. McGregor's bike needs some repairs and will be fixed by the time they reach Costa Rica. The ship they travel in with the bikes looks like a beaten-down vessel that raises genuine concerns about making the journey in one piece. The boat crew looks sharp and proactive while trying to make the show crew's journey as comfortable and safe as possible. The episode also introduces Nuqui, one of the wettest regions in the world where the ship quickly makes a pitstop to fuel up on essential supplies.

Ewan and Charley make their way to Peru from Bolivia, and the scenery is just beautiful. Ewan wanted to visit Machu Picchu since he was a kid and decides to show the world the Incan citadel set high in the Andes Mountains. Next up, they make their way to the Cutivireni, a community of Ashaninka people in the Amazon rainforest, with its carbon program to limit the magnitude or rate of global warming and its related effects.

Travel writer Simon Reeve embarks upon two long-distance journeys across Turkey, exploring this dramatic and beautiful country that now finds itself at the centre of world events. In this programme, he visits Istanbul and the beaches and crystal clear waters of the Aegean Sea, before ending up at the war-torn border with Syria.
In the region thought to have been the origin of the first vineyards, Simon meets a producer now trying to sell wine in a Muslim country with an increasingly conservative government. In Istanbul, he meets some of the people shaping modern Turkey, from loyal supporters of the nation's controversial and authoritarian president to the master builder constructing one of the world's largest mosques and the notorious billionaire cashing in on a Turkish property boom.
Along Turkey's famous Turquoise Coast, Simon has a taste of luxury at the country's most expensive hotel, but discovers an industry on its knees as war in Syria and deadly terror attacks keep millions of holidaymakers away.

Ewan McGregor and Charley Bormann are very close to finishing their journey. Discussions on security are still on the agenda; they cannot travel at night due to dangerous cartels. They will need to do many miles on a bus with space for the bikes inside. The team manage to get the bikes on after concerns they wouldn’t fit. Repairing and conditioning the bus is an achievement considering they did it in a few days.
Ewan and Charley get back on their bikes, and they head to their last border cross to enter the United States. After 12 hours in the border, the crew, Ewan and Charley make it to America. It’s an easy stretch to L.A. on their bikes. Ewan, the crew and family, finish the last leg. It’s done, they’ve managed to finish Long Way Up. It’s such an achievement. Episode 11 is a heartfelt finale, showcasing the end of an incredible journey from both Ewan, Charley, and the team that supported them.

Head beyond the Asteroid Belt for an out of this world experience. Welcome to Jupiter, home of high adrenaline adventure. Plunge into its mysterious depths. When you drop through the clouds it would get darker and hotter. At the center the temperatures are hotter than the surface of the sun and the pressures are unimaginably high.

For Charley Boorman and Ewan McGregor, their journey in the smooth Ecuadorian roads would most definitely have come as a relief after some rough terrain riding. Next up, they stop by one of the factories that make the famed Panama hats. One of the local producers explains that making them by hand takes roughly up to a month. At the other end, the crew on the Rivians make a dash for Central America where they have to ferry their trucks across as the Darién Gap blocks their path. On their way, they make a quick pitstop at one of the cacao factories to know more about cocoa production, one of the economic drivers of the country.