A ground-breaking new trial at Imperial College London sees, for the first time ever under controlled conditions, a psychedelic drug tested head-to-head against a standard antidepressant as a treatment for depression. The film follows a pioneering team of scientists and psychotherapists as they compare the effects of psilocybin (the active ingredient of magic mushrooms) with an antidepressant on a small group of participants with clinical depression.
This is scientific research at its most cutting edge. With over seven million people being prescribed antidepressants each year in England alone, this drug trial is an important milestone in understanding a completely different treatment for depression. How do psychedelic drugs measure up against the industry-standard antidepressants that have been popular since the 1990s? The empirical results of the trial are explored alongside the participants’ powerful lived experience.

In recent years, close study of the aging process has opened up new ways that could help us all live healthier for longer. Can we move beyond treating individual diseases, and instead treat the aging process itself? But would a longer life necessarily be a better life? A loose-knit group of researchers believe the real breakthrough is extending our health span - the period of life spent free of disease". Hear from Laura Deming, who dropped out of M.I.T. at the age of 14 and committed herself to finding and funding projects that can expand the human health span, and Dr. Brian Kennedy, whose work in the basic biology of aging has been crucial to the development of countless other researchers' work.

'What Makes Me?', explores the question of how the brain gives rise to our thoughts, emotions, our memories and personality. Philosophers and great thinkers have for millennia pondered the question of how physical stuff can give rise to mental processes. Last century, the new field of neuroscience joined the discussion, and Dr David Eagleman explains that to a neuroscientist, the answers to such questions lie in a deep understanding of the brain.

Hear firsthand from individuals struggling with addiction and follow the cutting-edge work of doctors and scientists as they investigate why addiction is not a moral failing, but a chronic, treatable medical condition. Easy access to drugs like heroin, fentanyl, and even prescription medications like OxyContin has fueled an epidemic of addiction - the deadliest in US history. Now, science is revealing how addiction affects the brain, and top experts are gathering evidence about how we should address our drug problem, from embracing evidence-based treatments, to rethinking public policies.

In just over 100 days, a new coronavirus has taken an unprepared world by storm, infiltrating every corner of the globe, sending entire nations into lockdown, killing thousands and infecting countless more. Across the world, governments are scrambling to react, hospitals are struggling to cope and an increasingly anxious public are starting to panic.
The world's media is awash with data, information and misinformation. But what are the facts? What is COVID-19 and why is this strain of coronavirus so dangerous? What happens in our bodies when the virus attacks? How does this compare to previous pandemics? What do all the the numbers really mean, and how can data modelling help us look for an exit strategy? This programme investigates the scientific facts and figures behind the biggest public health crisis in living memory, and explores the latest research from the frontline of the medical and scientific fightback.

Around the world, food allergies are surging to near-epidemic levels. Medicine is just beginning to understand why some people react to seemingly harmless foods. Scientists race to understand what's changed in our bodies, while farmers and chefs contend with new challenges.