Over a person's lifetime they are likely to be prescribed more than 14,000 pills. Antibiotics, cholesterol lowering tablets, anti-depressants, painkillers, even tablets to extend youth and improve performance in bed. These drugs perform minor miracles day after day, but how much is really known about them? Drug discovery often owes as much to serendipity as to science, and that means much is learnt about how medicines work, or even what they do, when they're taken. By investigating some of the most popular pills people pop, Horizon asks, how much can they be trusted to do what they are supposed to?

Professor Jim Al-Khalili investigates one of the most important concepts in the world today - information. He discovers how we harnessed the power of symbols, everything from the first alphabet to the electric telegraph through to the modern digital age. But on this journey he learns that information isn't just about human communication, it's woven very profoundly into the fabric of reality.

The Greek tale of Jason and the Golden Fleece has been told for 3,000 years. It's a classic hero's quest tale - a sort of ancient Greek mission impossible - in which the hero embarks on a sea voyage into an unknown land, with a great task to achieve. He is in search of a magical ram's fleece, which he has to find in order to reclaim his father's kingdom of Iolkos from the usurper King Pelias. Michael Wood discovers a story of heroism, treachery, love and tragedy that would make Hollywood proud.

Dr Thomas Dixon delves into the BBC's archive to explore the troubled relationship between religion and science. From the creationists of America to the physicists of the Large Hadron Collider, he traces the expansion of scientific knowledge and asks whether there is still room for God in the modern world. He looks at what happens when new scientific discoveries start to explain events that were once seen as the workings of God, and explains how some of our most famous scientists have seen God in the grandest laws of the universe. Finally, he finds intriguing evidence from brain science which hints that belief in God is here to stay.

Ferdinand Magellan and Juan Sebastian Elcano set sail to gain control of the global spice trade, but end up becoming the first expedition to circumnavigate the earth. The yearslong voyage—along with the suffering, the violence and the loss of life and property—were all in pursuit of a shorter route to the so-called Spice Islands (now the Maluku Islands) and their much-coveted aromatics.
The film puts in perspective the 16th century—the Age of Exploration, the Age of Discovery and the Age, problematically, of Colonialism. It also was an age of heroes. As the documentary insists, the journeys undertaken by the men whose names we learned in grade school and whose exploits straddled the 1400s and 1500s—including Ponce de Leon, Vasco da Gama, Lope de Aguirre and even Columbus—were about money, sometimes trade, sometimes plunder. But just as advances in medicine have often been propelled by war, knowledge about the world has been a byproduct of profit-seeking. Likewise, heroism.

In August 1977, the Big Ear Radio-telescope in Ohio received a strange signal from the Sagittarius constellation while searching for intelligent extra-terrestrial life. It had a duration of 72 seconds and an intensity 30 times higher than usual. Named the Wow signal, it is still being considered as one of the best examples of having being sent by intelligent extraterrestrial life. But, nothing has revolutionised the search of extra-terrestrial intelligent life as much as the recent discovery by the Kepler Satellite, of thousands of Earth-like planets where life could be possible. Join the debate with this stunning documentary, as we ask Is Anybody Out There?