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The dome that crowns Florence's great cathedral of Santa Maria del Fiore, the Duomo, is a masterpiece of Renaissance ingenuity and an enduring source of mystery. Still the largest masonry dome on earth, it is taller than the Statue of Liberty and weighs as much as an average cruise ship. Historians and engineers have long debated how its architect, Filippo Brunelleschi, kept the dome perfectly aligned and symmetrical as the sides rose and converged toward the center." More than four million bricks could collapse at any moment -- and we still don't understand how Brunelleschi prevented it. To test the latest theories, a team of U.S. bricklayers will help build an experimental "mini-Duomo" using period tools and techniques.

In this episode, Michael demonstrates how our society is built on our search to find the answer to what makes up everything in the material world. This is a story that moves from the secret labs of the alchemists and their search for gold by the stone of the philosophers to the creation of the world's first synthetic dye - Purple - and onto the invention of the transistor. This quest may seem abstract and highly theoretical. Yet it has delivered the greatest impact on humanity. By trying to answer this question, scientists have created theories from elements to atoms, and the strange concepts of quantum physics that underpin our modern, technological world.

In Bhutan, Palin finds himself back in the land of yaks for a last look at the high Himalaya. Trekking to Chomolhari base camp he meets a nomad with a penchant for yak songs before heading down to Paro to witness the Buddhist festival or Tsechu. In a bar in Thimphu, he discusses reincarnation and the pursuit of happiness with Benji and Khendum, two of the king's cousins, and en route to Bangladesh is taken by Benji to see the rare black-neck cranes. On his journey south through Bangladesh, Michael visits the ship-breaking beaches of Chittagong and grid-locked Dhaka. He meets a man who made a fortune in Birmingham in the poultry business, and a woman who lends money only to women. On a 1920s paddle steamer he is serenaded with the words of Bengal's Shakespeare, and he completes his epic Himalayan journey aboard a fishing boat that carries him out into the Bay of Bengal and a westering sun.

the final episode deals with plants that live in hostile environments. Attenborough visits Ellesmere Island, north of the Arctic Circle, to demonstrate that even in a place that is unconducive to life, it can be found. Algae and lichens grow in or on rock, and during summer, when the ice melts, flowers are much more apparent. However, they must remain close to the ground to stay out of the chilling wind. In the Tasmanian mountains, plants conserve heat by growing into 'cushions' that act as solar panels, with as many as a million individual shoots grouped together as one. Others, such as the lobelia in Mount Kenya, have a 'fur coat' of dense hairs on their leaves. The saguaro cactus in the Sonoran Desert flourishes because of its ability to retain vast amounts of water, which can't be lost through leaves because it has none. Many desert dwellers benefit from an accelerated life cycle, blooming rapidly within weeks after rainfall. Conversely, Mount Roraima is one of the wettest places on Earth. It is a huge sandstone plateau with high waterfalls and nutrients are continuously washed away, so plants have to adapt their diet if they are to survive. A bladderwort is shown invading a bromeliad. Inhabitants of lakes have other problems to contend with: those that dominate the surface will proliferate, and the Amazon water lily provides an apt illustration. Attenborough ends the series with an entreaty for the conservation of plant species.

Dawkins opines that the moral framework of religions is warped, and argues against the religious indoctrination of children. He discusses specifically the idea of religion seen as a virus in the sense of a meme. He begins by explaining how a child is genetically programmed to believe without questioning the word of authority figures, especially parents – the evolutionary imperative being that no child would survive by adopting a sceptical attitude towards everything their elders said. But this same imperative, he claims, leaves children open to infection by religion.

The honey badger looks like something you might buy in pet shop and give to children, but turns out to be one of the most violent and determined creatures ever to scuttle across the face of the earth. Nothing in the badger’s world-not even the badgers themselves-are safe from its remarkable ability to create havoc and cause harm. Like a meter long skunk with the brain of a shark the Honey Badger’s metabolism compels it to eat constantly and live on the run. Its diet is admirably inclusive ranging from insects to its own young. If an animal is too big to eat then the badger will fight it anyway, indeed it is this almost supernatural tenacity that compels you respect it, as well as yielding some of the most spectacular sequences in the film. Five foot long cobra sleeping in the top of tree? No problem, the badger scoots up and bites its head off. When an ailing badger is attacked by a full size leopard it takes the leopard over an hour to finish it off. When one is bitten in the face by a snake that can kill a man, it just lies down for a while and sleeps it off.