Magic mushrooms, long considered sacred by the Indigenous Mazatec in Mexico, become the subject of scientific studies measuring the intense effects of its Psilocybin and its potential therapeutic use.
In the second episode, we are introduced to Ben, who’s battled with crippling Obsessive-Compulsive Disorder (OCD) his entire life. When he had his firstborn, Ben’s life became full of panic attacks regarding his son’s safety, and he knew something had to change. Ben signed up for a psilocybin-assisted therapy clinical trial which was testing whether the psychedelic could help people with severe OCD. In the session under the influence of psilocybin, Ben felt decomposed and eventually grew into a tree. While living as a tree, he saw his human self, playing with his child. Though this sounds scary, from Ben’s perspective, it was beautiful. He was one with the universe, seeing himself in the ultimate third-person perspective. Finally, he saw how it could be different if he didn’t let his OCD control him. And several months out, all the symptoms disappeared.
Ben’s story is one of many told in this series, which gives hope that help is right around the corner for the millions who suffer —often in silence— with debilitating mental disorders. But Michael Pollan’s work is showcasing the success stories. Often, even in the most successful trials, psychedelic-assisted therapy only helps up to a third of people enter remission. More frequently, patients are helped —sometimes substantially— but they still suffer with their illnesses and some people aren’t helped at all.

Jacoba Ballard was an only child, conceived via donor sperm, who always dreamed of having a brother or sister. When an at-home DNA test led her to the discovery of not one but seven half-siblings, she realized that she had stumbled across a major finding.
Jacoba discovers a shocking scheme involving a former Indianapolis based fertility doctor, who, in a case of fertility fraud, used his own sperm to impregnate dozens of unsuspecting patients.

According to recent science the Neanderthals are not the knuckle-dragging apemen of popular imagination. The first part of the film investigates what Neanderthals looked like and how they lived in their Ice Age world. They were faster, smarter, better looking - and much more like us than we ever thought. Our guide is Ella Al-Shamahi, who enlists the skills of Andy Serkis, the master of performance capture, and a group of experts to investigate deeply Neanderthals appearance.
In the second part, Ella explores the fate of the Neanderthals - asking why they became extinct, and discovering how they live on inside of us today. About 2% of the DNA of most people is of Neanderthal origin - and it continues to affect us today. Neanderthals were a people who were supremely well adapted to their environment. But about 40,000 years ago they disappeared. Why?

In 1994, a thirteen year old boy disappeared from San Antonio, Texas. Three and a half years later, he is found alive and well thousands of miles away in a village in southern Spain with a story of kidnapping and torture. His family is overjoyed to bring him home. But all is not quite as it seems.
The boy bears many of the same distinguishing marks he always had, but why does he now have a strange accent? Why does he look so different? Any why doesn't the family seem to notice these glaring inconsistencies? It's only when an investigator starts asking questions that this strange tale takes an even stranger turn.

Charles Franz talks about his relationship with Father Maskell as a young student and reveals what he knows about the Church’s involvement with Maskell. Cathy’s sister sees the necklace given by Edgar Davidson and questions if it has significance.
Potential DNA and evidence could exist for the crime, and the police might be forced to act. A push for victims’ rights in Maryland goes to a committee but getting justice might be more difficult... and time doesn’t stand still for anyone.

After four decades of searching for him, they got a one hundred percent match to the Golden State Killer's DNA. As 72-year-old former police officer Joe DeAngelo's arrest unfolds in real time, chilling facts materialize that illuminate Michelle McNamara's prescience in her book's epilogue.