This highly anticipated psychedelic docuseries showcases what these substances teaches people about consciousness, dying, addiction, depression and transcendence. Filmmaker Alex Gibney and best-selling author Michael Pollan present it in four parts, each focused on a different mind-altering substance: LSD, psilocybin, MDMA, and mescaline. With Pollan as our guide, we journey to the frontiers of the new psychedelic renaissance -- and look back at almost-forgotten historical context -- to explore the potential of these substances to heal and change minds as well as culture.
The first chapter is a great introduction to the topic of LSD, from its 1943 origins to today's microdosing trend, for those who don’t already know a lot about the subject, and a fun and entertaining refresher on LSD for even experts in the field. The show takes us on a journey through the history of the powerful compound, from its discovery and its early medical use, to secret CIA mind-control studies, the counterculture and its banning, and finally to our current renaissance. It includes amazing clips of LSD’s inventor Albert Hofmann and powerful personal testimonies of individuals who have healed their suffering through LSD.

The Last Shaman James is an all American boy whose promising life is brought to a halt by acute depression. Turning his back on the most progressive western treatments and medicines, James discovers ayahuasca in search of healing in the Peruvian jungle. Over the course of 10 months venturing from Shaman to Shaman, James finds friendship, answers and a kind of redemption hidden deep in the Peruvian amazon. (Click CC for subtitles)

A ground-breaking new trial at Imperial College London sees, for the first time ever under controlled conditions, a psychedelic drug tested head-to-head against a standard antidepressant as a treatment for depression. The film follows a pioneering team of scientists and psychotherapists as they compare the effects of psilocybin (the active ingredient of magic mushrooms) with an antidepressant on a small group of participants with clinical depression.
This is scientific research at its most cutting edge. With over seven million people being prescribed antidepressants each year in England alone, this drug trial is an important milestone in understanding a completely different treatment for depression. How do psychedelic drugs measure up against the industry-standard antidepressants that have been popular since the 1990s? The empirical results of the trial are explored alongside the participants’ powerful lived experience.

Most planets we know of are so hellish, it seems impossible that anything could live. But it's amazing where life can take hold in the Earth. Astrobiologists look for simple single-celled microbes known as extremophiles in places as Danakil Depression, known in Ethiopia as 'The Gateway to Hell.'
In Episode 2, the fictional world is Janus, a planet in such a close orbit than its rotation is locked by the star's gravity and it always shows the same face to its sun. On one side of the planet, it's always daytime, a searing desert. On the other side, it's forever night, a frozen shadowland. Squeezed between the two, a sliver of perpetual twilight. Freezing meltwater flows from the cold side, carving canyons through the landscape. Deep in these canyons lives an extraordinary five-legged creature.

The final episode of this series looks at what happens to the brain when someone uses psychedelic drugs. It looks at how psychedelic drugs may be useful in dealing with anxiety in cancer survivors and serious depression. It explores the history of psychedelics and examines early medical experimentation with the drug. It also discussed why psychedelics were banned and examines how they affect the brain.

Modern headlines are claiming mindfulness may cure anxiety, depression, and a whole host of other health problems. How can this simple practice of watching your own breath change the way your brain works? And can that change your life? The fourth episode of the series looks at the power of mindfulness and meditation. It examines different kinds on meditation (transcendental, dynamic, and religious) and notes that they are different from mindfulness meditation (Satipatthana). Also it talks to neuroscientists who discuss what happens in the brain during meditation.