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The extraordinary story of Earth and why it is special and uniquely brimming with life among a largely unknown but harsh cosmic arena. It will be told by eight astronauts from their unique perspective of being away from Earth. In the first episode, Astronaut Chris Hadfield reveals the unlikely and unexpectedly interconnected systems that allow life on our planet to breathe.

The series highlights the major events which have shaped the Earth's history and allowed life to flourish. Follow Dr Stewart's personal journey to some of the most remote places on the planet. The atmosphere is Earth’s protective layer, cloaking us in a warm, oxygen-rich embrace and shielding us from the cold hostility of space. It acts as a natural greenhouse, keeping the Earth 51 degrees Fahrenheit warmer than it would otherwise be. Yet the atmosphere is also full of contradictions. It’s immensely powerful but at the same time highly sensitive. It’s destructive, yet it shelters us. It was created in part by the planet’s first organisms, and it continues to be essential for life.

The Taiga forest, on the edge of the Arctic, is a silent world of stunted conifers. The trees may be small but filming from the air reveals its true scale. A third of all trees on Earth grow here and during the short summer they produce enough oxygen to change the atmosphere. In California General Sherman, a giant sequoia, is the largest living thing on the planet, ten times the size of a blue whale. The oldest organisms alive are bristlecone pines. At more than 4,000 years old they pre-date the pyramids. But the baobab forests of Madagascar are perhaps the strangest of all.

This episodes the nature of the cosmos on the micro and atomic scales, using the Ship of the Imagination to explore these realms. Tyson describes some of the micro-organism that live within a dew drop, demonstrating parameciums and tardigrades. He proceeds to discuss how plants use photosynthesis via their chloroplasts to convert sunlight into chemical reactions that convert carbon dioxide and water into oxygen and energy-rich sugars. Tyson then discusses the nature of molecules and atoms and how they relate to the evolution of species. He uses the example set forth by Charles Darwin postulating the existence of the long-tongued Morgan's sphinx moth based on the nature of the comet orchid with pollen far within the flower. He further demonstrates that scents from flowers are used to trigger olfactory centers in the brain, stimulating the mind to threats as to aid in the survival of the species. Tyson narrates how Greek philosophers Thales and Democritus postulated that all matter was made up of combinations of atoms in a large number of configurations, and describes how carbon forms the basic building block for life on earth due to its unique chemical nature. Tyson explains on the basic atomic structure of protons, neutrons, and electrons, and the nature of nuclear fusion that occurs in most stars. He then discusses the existence of neutrinos that are created by these nuclear processes in stars, and that detecting such sub-atomic particles which normally pass through matter require subterranean facilities like the Super-Kamiokande that were used to detect neutrinos from the supernova SN 1987A in the Large Magellanic Cloud before light from the explosion were observed due to their ability to pass through matter of the dying sun. Tyson compares how neutrinos were postulated by Wolfgang Pauli to account for the conservation of energy from nuclear reactions in the same manner as Darwin's postulate on the long-tongued moth. Tyson concludes by noting that there are neutrinos from the Big Bang still existing in the universe but due to the nature of light, there is a "wall of infinity" that cannot be observed beyond.

Of all the wonders of the human body, there's one more mysterious than any other. Blood: five precious litres that keep us alive. Yet how much do we really know about this sticky red substance and its mysterious, life-giving force? Michael Mosley gives up a fifth of his own blood to perform six bold experiments". From starving it of oxygen to injecting it with snake venom, Michael reveals the extraordinary abilities of blood to adapt and keep us alive. Using specialist photography, the programme reveals the beauty in a single drop. Michael even discovers how it tastes when, in a television first, he prepares a black pudding with his own blood. Down the ages, our understanding of blood has been as much myth as science, but Michael reveals there might be truth in the old vampire legends, as he meets one of the scientists behind the latest research that shows young blood might be able to reverse the ageing process - the holy grail of modern medicine.