We now know that the brain - the organ that more than any other makes us human - is one of the wonders of the universe, and yet until the 17th century it was barely studied. The twin sciences of brain anatomy and psychology have offered different visions of who we are. Now these sciences are coming together and in the process have revealed some surprising and uncomfortable truths about what really shapes our thoughts, feelings and desires. And the search to understand how our brains work has also revealed that we are all - whether we realise it or not - carrying out science from the moment we are born.

Of all the wonders of the human body, there's one more mysterious than any other. Blood: five precious litres that keep us alive. Yet how much do we really know about this sticky red substance and its mysterious, life-giving force? Michael Mosley gives up a fifth of his own blood to perform six bold experiments". From starving it of oxygen to injecting it with snake venom, Michael reveals the extraordinary abilities of blood to adapt and keep us alive. Using specialist photography, the programme reveals the beauty in a single drop. Michael even discovers how it tastes when, in a television first, he prepares a black pudding with his own blood. Down the ages, our understanding of blood has been as much myth as science, but Michael reveals there might be truth in the old vampire legends, as he meets one of the scientists behind the latest research that shows young blood might be able to reverse the ageing process - the holy grail of modern medicine.

Professor Jim Al-Khalili discovers the intriguing story of how we discovered the rules that drive the universe. Energy is vital to us all, but what exactly is energy? In attempting to answer this question Jim investigates a strange set of laws that link together everything from engines to humans to stars. It turns out that energy, so critical to daily existence, actually helps us make sense of the entire universe.

Even after thousands of years of ice crushing the northern hemisphere and temperatures of 20 degrees lower than those of today, many of the great giants of the ice age still walked the earth. It was only when the world had warmed up again that mammoths, woolly rhinos, sabre-toothed cats, giant ground sloths and glyptodonts finally became extinct. Professor Alice Roberts sets off on her last voyage back to the Ice Age to discover why.

Marcus Du Sautoy wants to find out how close we are to creating machines that can think like us: robots or computers that have artificial intelligence. His journey takes him to a strange and bizarre world where AI is now taking shape. Marcus meets two robots who are developing their own private language, and attempts to communicate to them. He discovers how a super computer beat humans at one of the toughest quiz shows on the planet, Jeopardy". And finds out if machines can have creativity and intuition like us. Marcus is worried that if machines can think like us, then he will be out of business. But his conclusion is that AI machines may surprise us with their own distinct way of thinking.

In the last few years, the Red Planet has yielded up many new clues that life may have once existed there...and may even exist there today. There is now have proof that water once flowed on the surface, that Mars once had lakes, and that the frozen poles are mostly water, not carbon dioxide as previously thought. Mars has snow--an aurora--and lightning generated by dust storms. Most intriguing of all are the seasonal plumes of methane that just may point to bacteria living below the surface.