The story of how the secret of life has been examined through the prism of the most complex organism known - the human body. It begins with attempts to save the lives of gladiators in Ancient Rome, unfolds with the macabre work and near-perfect drawings of Leonardo in the Renaissance, through the idea of the 'life force' of electricity, to the microscopic world of the cell. It reveals how a moral crisis unleashed by work on the nuclear bomb helped trigger a great breakthrough in biology - understanding the structure and workings of DNA.

This episode explores the palaeogeography of Earth over millions of years, and its impact on the development of life on the planet. Tyson starts by explaining that the lignin-rich trees evolved in the Carboniferous era about 300 million ago, then explains on the nature of plate tectonics that would shape the landmasses of the world and the asteroid impact that initiated the Cretaceous–Paleogene extinction event, leaving small mammals as the dominate species on earth. Earth's landmasses are expected to change in the future and postulates what may be the next great extinction event.

For the animals in the polar regions, autumn means dramatic battles and epic journeys. Time is running out - the Arctic Ocean is freezing over and the sea ice is advancing at 2.5 miles per day around Antarctica. Polar bears gather in large numbers on the Arctic coast as they wait for the return of the ice. Soon, tempers fray and violent sparring contests break out. Meanwhile 2,000 beluga whales head for one special estuary, a gigantic 'whale spa' where they will thrash their snow-white bodies against the gravel and exfoliate. Inland, the tundra undergoes a dramatic transformation from green to fiery red. Here, musk ox males slam head-first into each other with the force of a 30mph car crash as they struggle to defend their harems. Frisky young caribou males play a game of 'grandma's footsteps' as they try to steal the boss's female. Down in Antarctica, Adelie penguin chicks huddle together in creches. When a parent returns from fishing, it leads its twins on a comical steeplechase - sadly there's only enough for one, so the winner gets the meal. Two months later and the chicks are fully feathered apart from downy Mohican hairdos - they're ready to take their first swim - reluctantly though, as it seems penguins are not born with a love of water! And with good reason - a leopard seal explodes from the sea and pulls one from an ice floe, a hunting manoeuvre that has never been filmed before. As winter approaches and everyone has left, the giant emperor penguin arrives and makes an epic trek inland to breed. The mothers soon return to the sea leaving the fathers to hold the eggs and endure the coldest winter on earth.

Long ago, two species of human beings coexisted on Earth until competition drove one of them to extinction. This program, set in the southwest of France 35,000 years ago, reconstructs the life in the Neanderthal world at the time Cro-Magnons first entered the scene. All aspects of Neanderthal clan life are examined, including tool- and weapon-making, hunting and gathering, health and healing, childbirth, rituals, and making fire. Footage of skeletal remains and the scholarly research of eminent paleontologist Chris Stringer and Oxford University's Paul Pettitt support the documentary.

Examines the impact of racism in the 20th century. By 1900 European colonial expansion had reached deep into the heart of Africa. Under the rule of King Leopold II, the Belgian Congo was turned into a vast rubber plantation. Men, women and children who failed to gather their latex quotas would have their limbs dismembered. The country became the scene of one of the century's greatest racial genocides, as an estimated 10 million Africans perished under colonial rule.

After eight grueling years of hunting in the hot, wind-scoured desert of central Africa, an international team of researchers has uncovered one of the most sensational fossil finds in living memory: the well-preserved 7 million years old skull of a chimp-size animal, probably a male, that doesn't fit any known species. According to paleontologist Michel Brunet of the University of Poitiers in France, whose team reported the find in Nature last week, there is no way it could have been an ape of any kind. It was almost certainly a hominid — a member of a subdivision of the primate family whose only living representative is modern man.