The Last Shaman James is an all American boy whose promising life is brought to a halt by acute depression. Turning his back on the most progressive western treatments and medicines, James discovers ayahuasca in search of healing in the Peruvian jungle. Over the course of 10 months venturing from Shaman to Shaman, James finds friendship, answers and a kind of redemption hidden deep in the Peruvian amazon. (Click CC for subtitles)

The extraordinary inside story of the biggest scientific challenge of our age – following a small band of vaccine scientists around the world who took on Covid-19 and ultimately delivered the weapon to beat it.
As news of the coronavirus broke around the globe, a small group of scientists jumped into action to tackle one of the greatest medical challenges of our time: to create a vaccine against a virus no-one had ever seen before and to do so in record time, all during a deadly, global pandemic.

A powerful movement is exploiting our fears, persuading some to believe the vaccine was designed to control or even kill us. Who are the people behind the international anti-Covid-vaccine movement and why are they doing it? In the anti-vax movement - where is the money? The money comes from a small but very well-heeled network of donors and philanthropists who fund anybody reinforcing their opinions.
The film is a journey inside the astonishing world of the anti-vaxxers.

A ground-breaking new trial at Imperial College London sees, for the first time ever under controlled conditions, a psychedelic drug tested head-to-head against a standard antidepressant as a treatment for depression. The film follows a pioneering team of scientists and psychotherapists as they compare the effects of psilocybin (the active ingredient of magic mushrooms) with an antidepressant on a small group of participants with clinical depression.
This is scientific research at its most cutting edge. With over seven million people being prescribed antidepressants each year in England alone, this drug trial is an important milestone in understanding a completely different treatment for depression. How do psychedelic drugs measure up against the industry-standard antidepressants that have been popular since the 1990s? The empirical results of the trial are explored alongside the participants’ powerful lived experience.

In the second part and conclusion, a spotlight on the mass marketing of the synthetic opioid fentanyl examines the connections between drug manufacturers and government policy. Video of sales retreats and promotional material reveals a deep cynicism among company employees and a disregard for the widespread, nefarious corporate practices.

This series is a searing indictment of Big Pharma and the political operatives and government regulations that enable over-production, reckless distribution and abuse of synthetic opiates. Exploring the origins, extent and fallout of one of the most devastating public health tragedies of our time, with half a million deaths from overdoses this century alone, the film reveals that America's opioid epidemic is not a public health crisis that came out of nowhere.
In the first part, a look at how Purdue Pharma worked with the FDA to get OxyContin approved for wider use, promoting the highly profitable pain medication's safety without sufficient evidence, and creating a campaign to redefine pain and how it's treated.