Over a person's lifetime they are likely to be prescribed more than 14,000 pills. Antibiotics, cholesterol lowering tablets, anti-depressants, painkillers, even tablets to extend youth and improve performance in bed. These drugs perform minor miracles day after day, but how much is really known about them? Drug discovery often owes as much to serendipity as to science, and that means much is learnt about how medicines work, or even what they do, when they're taken. By investigating some of the most popular pills people pop, Horizon asks, how much can they be trusted to do what they are supposed to?

Dr Michael Mosley and Professor Alice Roberts investigate if male and female brains really are wired differently. New research suggests that the connections in men and women's brains follow different patterns, patterns which may explain typical forms of male and female behaviour. But are these patterns innate, or are they shaped by the world around us?" Using a team of human lab rats and a troop of barbary monkeys, Michael and Alice test the science and challenge old stereotypes. They ask whether this new scientific research will benefit both men and women - or whether it could drive the sexes even further apart.

Are the wealthy just born in the right place at the right time? Are the poor victims of a system designed to keep them down? Or do physics and biology determine who is rich and who is poor? Throughout history, distribution of wealth is governed by hidden forces: DNA, environmental stress, patterns of human migration and even the laws of thermodynamics! Nature seems to demand winners and losers in life. But does this mean greed is king, and the rich can take what they want? Or is cooperation – between microorganisms, monkeys, and humans – more essential to survival of a species?

Imagine if one minute from now, every single person on Earth disappeared. All of us. Human history just stopped. What would happen to the world without us? Aftermath: Population Zero features what scientists and others speculate the earth, animal life, and plant life might be like if humanity no longer existed, as well as the effect that humanity's disappearance would have on the artefacts of civilization. this documentary is inspired by Alan Weisman's The World Without Us.

It's a mystery mankind has struggled to solve since the beginning of history - is space infinite or might there be great cosmic border where everything ends? Groundbreaking cosmology and state of the art space telescopes, now suggest the Universe has a finite size and a unique shape. If this is true, there must be an edge to the Universe, and beyond that edge, there could exist a world beyond our wildest dreams.

If you had less than one second to make a life-or-death decision to shoot a man who might be armed with a lethal weapon, what would you do? Would the ethnicity of the man affect your decision? Are you sure? The outcome – whatever your race – will surprise you. Brain imaging studies are showing that negative cultural stereotypes hijack everyone’s subconscious decision-making. But some science says we can overcome bigotry through exposure, self-awareness and flexible social networks… and, most controversially of all, ultra-violent video games!