During 1964-1969 both sides now plan to put a man on the Moon - while the Soviets struggle, the Americans pull ahead in the space race with Project Gemini, but then suffer a disaster with the Apollo 1 fire. The Soviet space programme suffers its own blows: Sergei Korolev dies when his heart fails during an operation, Soyuz 1 crashes and kills cosmonaut Vladimir Komarov, and their planned moon rocket, the N-1 rocket, fails to successfully launch. In America, von Braun has difficulties with the Saturn V, but they are overcome, and the rocket successfully launches the first manned lunar mission, Apollo 8, and the first manned lunar landing, Apollo 11.

The story begins with Tyson sitting at a campfire, and telling how the wolf changed through artificial selection, and selective breeding into the dog breeds around today. He then enters the Ship of Imagination, and explains natural selection with the process that helped to create the polar bears. Along the way he talks about DNA, genes and mutation. Next he goes to a forest and describes the Tree of life, this leads him to discussing the evolution of the eye. He then discusses extinction, by going to a monument called the Halls of Extinction, dedicated to the broken branches of the tree of life. Explaining the five great Extinction events. He then tells how some life has survived, and then focuses on the tardigrade. From there he talks about what other kinds of life might have been created on other worlds. He then goes to Saturn's moon Titan. From there he speculates about life and how it first began. He then returns to Earth and tells about abiogenesis and how life changed and evolved. The show ends with an animated sequence from the original series of life's evolution from one cell to humans.

Does life exist on other planets? Astrobiology is a visionary new science that searches for life in space by combining the disciplines of astronomy, biology and geology. How did life evolve on Earth? What will life look like on other planets? These and other pertinent questions will be answered by a diverse group of scientists. Viewers will visit the Pilbara region of West Australia where the oldest evidence of life on Earth has been discovered. Travel to the moons of Jupiter and Saturn to test a theory that life could exist in the clouds of Venus. Finally, watch as experiments are done to see if life exists on exoplanets, earth-like planets beyond our solar system.

It's a voyage of exploration like no other - to Titan, Saturn's largest moon and thought to resemble our own early Earth. For a small team of British scientists this would be the culmination of a lifetime's endeavour - the flight alone, some 2 billion miles, would take a full seven years. This is the story of the space probe they built, the sacrifices they made and their hopes for the landing. Would their ambitions survive the descent into the unknown on Titan's surface?