The story begins with Tyson sitting at a campfire, and telling how the wolf changed through artificial selection, and selective breeding into the dog breeds around today. He then enters the Ship of Imagination, and explains natural selection with the process that helped to create the polar bears. Along the way he talks about DNA, genes and mutation. Next he goes to a forest and describes the Tree of life, this leads him to discussing the evolution of the eye. He then discusses extinction, by going to a monument called the Halls of Extinction, dedicated to the broken branches of the tree of life. Explaining the five great Extinction events. He then tells how some life has survived, and then focuses on the tardigrade. From there he talks about what other kinds of life might have been created on other worlds. He then goes to Saturn's moon Titan. From there he speculates about life and how it first began. He then returns to Earth and tells about abiogenesis and how life changed and evolved. The show ends with an animated sequence from the original series of life's evolution from one cell to humans.

In the third programme of the series, Aleks gives the lowdown on how, for better and for worse, commerce has colonized the web - and reveals how web users are paying for what appear to be 'free' sites and services in hidden ways. Joined by some of the most influential business leaders of today's web, including Eric Schmidt (CEO of Google), Chad Hurley (CEO of YouTube), Bill Gates, Martha Lane Fox and Reed Hastings (CEO of Netflix), Aleks traces how business, with varying degrees of success, has attempted to make money on the web. She tells the inside story of the gold rush years of the dotcom bubble and reveals how retailers such as Amazon learned the lessons. She also charts how, out of the ashes, Google forged the business model that has come to dominate today's web, offering a plethora of highly attractive, overtly free web services, including search, maps and video, that are in fact funded through a sophisticated and highly lucrative advertising system which trades on what we users look for. Aleks explores how web advertising is evolving further to become more targeted and relevant to individual consumers. Recommendation engines, pioneered by retailers such as Amazon, are also breaking down the barriers between commerce and consumer by marketing future purchases to us based on our previous choices. On the surface, the web appears to have brought about a revolution in convenience. But, as companies start to build up databases on our online habits and preferences, Aleks questions what this may mean for our notions of privacy and personal space in the 21st century

Cannabis is the world's favourite drug, but also one of the least understood. Can cannabis cause schizophrenia? Is it addictive? Can it lead you on to harder drugs? Or is it simply a herb, an undervalued medicine? Addiction specialist Dr John Marsden discovers that modern science is finally beginning to find answers to these questions. John traces the cannabis plants' birthplace in Kazakhstan; finds the origins of our sensitivity to cannabis in the simple sea squirt; and finds out just what it does to our brains. He meets people who have been changed by this drug in drastically different ways - from those whose lives have been shattered to those who lives have been revived.

Brian explores the physics of the size of life through some close encounters with Australia's wildlife. From swimming with great white sharks to tracking red kangaroos, he discovers that the size you are profoundly affects the life you lead and, ultimately, how long you have to enjoy it.

Some of the world's leading physicists believe they have found startling new evidence showing the existence of universes other than our own. One possibility is that the universe is so vast that an exact replica of our solar system, our planet and ourselves exists many times over. These Doppelganger Universes exist within our own Universe; in what scientist now call "The Multiverse." If proof is found it will change our lives, our minds, our planet, our science and our universe.

The third episode is devoted to the ways in which plants reproduce. Pollen and a stigma are the two components needed for fertilisation. Most plants carry both these within their flowers and rely on animals to transport the pollen from one to the stigma of another. To do this, they attract their couriers with colour, scent and nectar. It isn't just birds that help pollination: some mammals and reptiles also do so. However, it is mostly insects that are recruited to carry out the task. To ensure that pollen is not wasted by being delivered to the wrong flower, some species of plant have developed exclusive relationships with their visitors, and the gentian and its attendant carpenter bees is one example. Since pollen can be expensive to produce in terms of calories, some plants, such as orchids, ration it by means of pollinia and a strategically placed landing platform. Other orchids offer no reward for pollination, but instead mislead their guests by mimicking their markings and aroma, thus enticing males to 'mate' with them (Pseudocopulation). The most extreme fertilisation method is one of imprisonment, and one plant that uses it is the dead horse arum. It is often found near gull colonies, and mimics the appearance and smell of rotting flesh. Blow-flies are attracted to it, and are forced to stay the night before being allowed to depart in the morning, laden with pollen. Finally, Attenborough introduces the world's largest inflorescence: that of the titan arum.