This film is a multi-dimensional journey through the city that was once the cradle of the Italian Renaissance. Get an exclusive tour through the most beautiful and representative works of art of the period from Michelangelo and Brunelleschi, to Leonardo and Botticelli, with a detailed central chapter dedicated to the very treasure house containing their masterpieces: the Uffizi Gallery. This also includes the breathtaking 'Adoration of the Mag' by Leonardo Da Vinci, which, after several years of restoration, will be brought back to life and unveiled in this worldwide exclusive premiere on the big screen.

Back one million years ago, South America was a continent of exotic oversized creatures found nowhere else on Earth - huge terror birds, giant ground sloths and spiky-tailed relatives of the armadillo as big as cars. The deadliest animal of them all was smilodon, the largest of the sabre-tooth cats, with canines like carving knives. The programme follows the fortunes of an individual male, Half Tooth. Ousted from his clan by a pair of rival males, his life suddenly becomes a struggle to survive in this alien world.

Moving on to Ethiopia 3.2 million years ago, we witness the beginnings of mankind via a group of australopithecus - a type of ape which, like us, walks upright on two legs. But unlike us, these early members of the human family weren't predators, they were prey. Things get worse for the group as they are hunted by a sabre-tooth cat called dinofelis and fall victim to other dangers such as malaria, rival australopithecus and a rampaging 14-tonne deinotherium.

Reporter Dr. Graham Phillips examines the effects of meditation in his own life, and the medical evidence of how it affects those who practice it. Can meditation literally make your brain younger?

In the third part of his journey into the history of Christianity, Professor Diarmaid MacCulloch charts Orthodoxy's extraordinary fight for survival. After its glory days in the eastern Roman Empire, it stood right in the path of Muslim expansion, suffered betrayal by crusading Catholics, was seized by the Russian tsars and faced near-extinction under Soviet communism. MacCulloch visits the greatest collection of early icons in the Sinai desert, a surviving relic of the iconoclastic crisis in Istanbul and Ivan the Terrible's cathedral in Moscow to discover the secret of Orthodoxy's endurance.

Over one billion Christians look to Rome, more than half of all Christians on the planet. But how did a small Jewish sect from the backwoods of 1st-century Palestine, which preached humility and the virtue of poverty, become the established religion of western Europe - wealthy, powerful and expecting unfailing obedience from the faithful? Amongst the surprising revelations, Professor MacCulloch tells how confession was invented by monks on a remote island off the coast of Ireland, and how the Crusades gave Britain the university system. Above all, it is a story of what can be achieved when you have friends in high places.