A ground-breaking new trial at Imperial College London sees, for the first time ever under controlled conditions, a psychedelic drug tested head-to-head against a standard antidepressant as a treatment for depression. The film follows a pioneering team of scientists and psychotherapists as they compare the effects of psilocybin (the active ingredient of magic mushrooms) with an antidepressant on a small group of participants with clinical depression.
This is scientific research at its most cutting edge. With over seven million people being prescribed antidepressants each year in England alone, this drug trial is an important milestone in understanding a completely different treatment for depression. How do psychedelic drugs measure up against the industry-standard antidepressants that have been popular since the 1990s? The empirical results of the trial are explored alongside the participants’ powerful lived experience.

In the second part and conclusion, a spotlight on the mass marketing of the synthetic opioid fentanyl examines the connections between drug manufacturers and government policy. Video of sales retreats and promotional material reveals a deep cynicism among company employees and a disregard for the widespread, nefarious corporate practices.

This series is a searing indictment of Big Pharma and the political operatives and government regulations that enable over-production, reckless distribution and abuse of synthetic opiates. Exploring the origins, extent and fallout of one of the most devastating public health tragedies of our time, with half a million deaths from overdoses this century alone, the film reveals that America's opioid epidemic is not a public health crisis that came out of nowhere.
In the first part, a look at how Purdue Pharma worked with the FDA to get OxyContin approved for wider use, promoting the highly profitable pain medication's safety without sufficient evidence, and creating a campaign to redefine pain and how it's treated.

Some 30 million Americans have sent their DNA to be analysed by companies like 23andMe and AncestryDNA. But what happens once the sample is in the hands of testing companies, and how accurate are their results? The film explores the power of genetic data to reveal family connections, ancestry, and health risks—and even solve criminal cold cases.

The film is a descriptive time-lapse journey about the magical, mysterious and medicinal world of fungi and their power to heal, sustain an contribute to the regeneration of life on Earth that began 3.5 billion years ago.
Imagine an organism that feeds you, heals you, reveals secrets of the universe and could help save the planet. You'll see it through the eyes of mycologists, like renowned Paul Stamets, about the unlimited potential of fungi in the fields of food, medicine, expanding consciousness, bioremediation, neurogenesis and treating end-of-life anxiety.

Trailblazing scientists are making ground-breaking discoveries in the rapidly evolving world of genetic engineering. Technologies like CRISPR are making it possible to quickly and cheaply change the DNA of all living things, including humans. Today, genes can be edited almost as easily as words on a computer screen. This new ability to alter our DNA holds the promise of curing disease , saving threatened species, solving the problem of world hunger and maybe even obtaining human perfection. But will the promise be fulfilled and at what cost?
The ability to gain control of our DNA is ground-breaking and revolutionary but there are varying opinions among scientists as to how the technology should be used responsibly. This documentary follows the science as it progresses at a breakneck speed.