Over a person's lifetime they are likely to be prescribed more than 14,000 pills. Antibiotics, cholesterol lowering tablets, anti-depressants, painkillers, even tablets to extend youth and improve performance in bed. These drugs perform minor miracles day after day, but how much is really known about them? Drug discovery often owes as much to serendipity as to science, and that means much is learnt about how medicines work, or even what they do, when they're taken. By investigating some of the most popular pills people pop, Horizon asks, how much can they be trusted to do what they are supposed to?

Dr Michael Mosley and Professor Alice Roberts investigate if male and female brains really are wired differently. New research suggests that the connections in men and women's brains follow different patterns, patterns which may explain typical forms of male and female behaviour. But are these patterns innate, or are they shaped by the world around us?" Using a team of human lab rats and a troop of barbary monkeys, Michael and Alice test the science and challenge old stereotypes. They ask whether this new scientific research will benefit both men and women - or whether it could drive the sexes even further apart.

It's a mystery mankind has struggled to solve since the beginning of history - is space infinite or might there be great cosmic border where everything ends? Groundbreaking cosmology and state of the art space telescopes, now suggest the Universe has a finite size and a unique shape. If this is true, there must be an edge to the Universe, and beyond that edge, there could exist a world beyond our wildest dreams.

If you had less than one second to make a life-or-death decision to shoot a man who might be armed with a lethal weapon, what would you do? Would the ethnicity of the man affect your decision? Are you sure? The outcome – whatever your race – will surprise you. Brain imaging studies are showing that negative cultural stereotypes hijack everyone’s subconscious decision-making. But some science says we can overcome bigotry through exposure, self-awareness and flexible social networks… and, most controversially of all, ultra-violent video games!

They are the most powerful objects in the universe. Nothing, not even light, can escape the gravitational pull of a black hole. Astronomers now think there are billions of them out in the cosmos, swallowing up planets, even entire stars in violent feeding frenzies. New theoretical research into the twisted reality of black holes suggests that three-dimensional space could be an illusion. That reality actually takes place on a two-dimensional hologram at the edge of the universe.

SETTING: 80 million years ago in the South American forests of Patagonia. The world is a very dangerous place for tiny hatchlings like Alpha, a female saltasaur. Follow Alpha along the road of her growth years, from before her birth through asolescence and on to adulthood, as she learns how to survive and beat the odds.