This series takes viewers on a journey to the frontiers of science, where researchers are tackling some of the biggest questions about life and the cosmos. The universe is hiding something. In fact, it is hiding a lot. Everything we experience on Earth, the stars and galaxies we see in the cosmos—all the 'normal' matter and energy that we understand—make up only 5% of the known universe. The other 95% is made up of two mysterious components: 'dark matter' and 'dark energy.' We can’t see them, but we know they’re there. And what’s more —these two shadowy ingredients are locked in an epic battle to control the very fate of the universe.
Now, scientists are trying to shed light on the so-called 'dark sector' as the latest generation of detectors rev up, and powerful telescopes peer deeper into space than ever before to observe how it behaves. Will the discoveries help reveal how galaxies formed? In the series finale, Nova Wonders journeys to the stars and back to investigate what we know —and don’t know. Find out how scientists are discovering new secrets about the history of the universe, and why they’re predicting a shocking future.

The second part, Nothing, explores science at the very limits of human perception, where we now understand the deepest mysteries of the universe lie. Professor Jim Al-Khalili sets out to answer one very simple question - what is nothing? His journey ends with perhaps the most profound insight about reality that humanity has ever made. Everything came from nothing. The quantum world of the super small shaped the vast universe we inhabit today, and Jim can prove it.

Mark Oliver Everett, singer of the band EELS, on his quest to get to know his later father, quantum physicist Hugh Everett III, who invented the Many Worlds theory. The film follows Mark on his journey across America, where he meets old friends and colleagues of his father. Hugh died of a heart attack in his home in 1982, where his body was found by 19-year-old Mark. Even though they had lived in the same house, the two of them were alienated. Only by entering the paradoxical world of quantum mechanics can Mark hope to understand why he was such a stranger to his own father.

Professor Jim Al-Khalili investigates the most accurate and yet perplexing scientific theory ever - quantum physics. At the beginning of the 20th century scientists were led into the hidden workings of matter, into the sub-atomic building blocks of the world around us. They discovered phenomena unlike any encountered before - a realm where things can be in many places at once, where chance and probability call the shots and where reality appears to only truly exist when we observe it. Albert Einstein hated the idea that nature, at its most fundamental level, is governed by chance. Jim reveals how, in the 1930s, Einstein thought he'd found a fatal flaw in quantum physics because it implies that sub-atomic particles can communicate faster than light in defiance of the theory of relativity. In the 1960s the scientist John Bell showed there was a way to test if Einstein was right and quantum mechanics was actually mistaken. Jim repeats this critical experiment - with shocking results.

Comedian Ben Miller returns to his roots as a physicist to try to answer a deceptively simple question: what is one degree of temperature? His quest takes him to the frontiers of current science as he meets researchers working on the hottest and coldest temperatures in the universe, and to a lab where he experiences some of the strangest effects of quantum physics - a place where super-cooled liquids simply pass through solid glass. Plus, Ben installs his very own Met office weather station at home. Ben's investigations in this personal and passionate film highlight the importance of measurement and accuracy in the 21st century.

Richard Dawkins examines the growing suspicion the public has for science-based medicine, despite its track record of successes like the germ theory of disease, vaccines, antibiotics and increased lifespan. He notes a fifth of British children are currently not immunised against measles, mumps and rubella, attributing it to fears arising from a highly controversial report linking the vaccine with autism. Dawkins criticizes the growing field of alternative medicine which does not pass the same objective and statistical rigour as scientifically derived treatments using controlled double-blind studies. Without verifiable evidence, alternative therapies must rely on biased anecdotes and word of mouth to perpetuate. Dawkins observes these treatments have fanciful rationales and rituals behind them, with many alternative treatments employing pseudoscientific jargon such as "energy", "vibration" or "quantum theory" to give themselves greater credence to patients.