Diseases

Of all the diseases that plague humankind, malaria has put up one of the longest, toughest fights. More than 200 million people fall ill and 600,000 die of it every year, making it among the world’s deadliest diseases. The vast majority of those fatalities are young children - an average of one child every minute. But medical science may now be at an exciting turning point.
Filmed with intimate access to key scientists on four continents, this documentary tells the inside story of the development of a new malaria vaccine that could change the very nature of the fight. It's hoped that the vaccine, dubbed R21/Matrix-M and developed by many of the same team behind the Oxford/AstraZeneca Covid-19 vaccine, will be the first to meet the World Health Organization’s target of 75 per cent efficacy.

In an enthralling documentary, Dan Snow and archaeologist Raksha Dave delve into the catastrophic impact of the Black Death on Britain 700 years ago, a pandemic that extinguished around half of the population, or three million people. The duo embarks on a journey to trace the origins and merciless spread of the plague, starting from its arrival on Britain's South coast in June 1348, through the bustling trade routes that brought the disease to Melcombe Regis, Dorset. Their investigation takes them to various hotspots of the outbreak, including the Old Operating Theatre in London and Wildwood Animal Sanctuary in Kent, where they explore the role of rats in dispersing the bubonic plague. Through dramatic reconstructions and visits to places like Nottingham University's biomedical laboratories, they uncover the rapid spread and deadly impact of the plague, offering a month-by-month account of how it ravaged the country, decimating cities, towns, and villages alike.
The documentary not only showcases the horrific symptoms and desperate attempts at cures through brutal medical practices of the time but also leverages cutting-edge research to explain why the Black Death remains the deadliest pandemic in history. The personal stories of victims, from princes to paupers, are brought to light, revealing the indiscriminate nature of the disease. Dan's visit to Canterbury Cathedral and Raksha's investigation into the recent discovery of mass graves beneath a tranquil London square underline the widespread desperation and devastation. Their journey through the history of the Black Death, culminating in the discovery of its indiscriminate toll and the unveiling of mass graves in London, not only sheds light on the darkest chapters of British history but also ignites a profound understanding of the tragedy, making a compelling case for why this documentary is a must-watch for anyone interested in the profound impacts of pandemics on human society.

Follow three women at risk of developing Alzheimer’s and join a groundbreaking study to try to prevent the disease, while sharing their ups and downs, anxiously watching for symptoms, and hoping they can make a difference. Barb, Sigrid, and Karen all had mothers with Alzheimer’s and witnessed first hand the devastation wrought by the disease, not only on the mind and body, but on patients’ families.

This is the dramatic global story of the first year of COVID-19, tracing the devastation caused by the spread of the virus across four continents. The way in which this coronavirus became COVID-19, transmission from animals to humans, is going on all the time. Habitat loss and live animal trading around the world that foster this is continuing. And therefore, we've got to expect that this will happen again.

The Coronavirus disease 2019 (COVID-19) has spread globally since 2019, resulting in a pandemic. While the majority of cases result in mild symptoms, some progress to pneumonia and multi-organ failure. The deaths per number of diagnosed cases is estimated at between 1% and 5% but varies by age and other health conditions.
In this special on the coronavirus, we're with health staff working on the front-line of the Covid-19 crisis - as well as the scientists, economists and virology experts who can answer the question... Coronavirus: Are We Doing Enough?

In just over 100 days, a new coronavirus has taken an unprepared world by storm, infiltrating every corner of the globe, sending entire nations into lockdown, killing thousands and infecting countless more. Across the world, governments are scrambling to react, hospitals are struggling to cope and an increasingly anxious public are starting to panic.
The world's media is awash with data, information and misinformation. But what are the facts? What is COVID-19 and why is this strain of coronavirus so dangerous? What happens in our bodies when the virus attacks? How does this compare to previous pandemics? What do all the the numbers really mean, and how can data modelling help us look for an exit strategy? This programme investigates the scientific facts and figures behind the biggest public health crisis in living memory, and explores the latest research from the frontline of the medical and scientific fightback.