What is the universe made of? If you answered stars, planets, gas and dust, you'd be dead wrong. Thirty years ago, scientists first realized that some unknown dark substance was affecting the way galaxies moved. Today, they think there must be five times our understanding of the universe and the nature of reality itself has drastically changed over the last 100 years - and it's on the verge of another seismic shift. In a 17-mile-long tunnel buried 570 feet beneath the Franco-Swiss border, the world's largest and most powerful atom smasher, the Large Hadron Collider, is powering up. Its goal is nothing less than recreating the first instants of creation, when the universe was unimaginably hot and long-extinct forms of matter sizzled and cooled into stars, planets, and ultimately, us. These incredibly small and exotic particles hold the keys to the greatest mysteries of the universe. What we find could validate our long-held theories about how the world works and what we are made of -- or, all of our notions about the essence of what is real will fall apart.

Professor Brian Cox visits Geneva to take a look around Cern's Large Hadron Collider before this vast, 27km long machine is sealed-off and the experiment to create the simulation of a black hole begins. When it's up and running, it will be capable of creating the conditions that existed just a billionth of a second after the Big Bang. Brian joins the scientists who hope that the LHC will change our understanding of the early universe and solve some of its mysteries.