Twenty years on from the invention of the world wide web, this major new series takes stock of its profound impact – how, for better and for worse, the digital revolution is reshaping our lives. Dr Aleks Krotoski explores the meaning of a phenomenon that is transforming everything, from how we learn to how we shop, vote and make friends. With a quarter of the planet connected so far, this series examines what is in store for the remaining 75 per cent of the world's population as they come online." In the first part series, Aleks charts the extraordinary rise of blogs, Wikipedia and YouTube, and traces an ongoing clash between the freedom the technology offers us, and our innate human desire to control and profit. Dr Aleks Krotoski looks at how it is reshaping almost every aspect of our lives. Joined by some of the web's biggest names - including the founders of Facebook, Twitter, Amazon, Apple and Microsoft, and the web's inventor - she explores how far the web has lived up to its early promise.

Here, Aleks charts how the Web is forging a new brand of politics, both in democracies and authoritarian regimes. With contributions from Al Gore, Martha Lane Fox, Stephen Fry and Bill Gates, Aleks explores how interactive, unmediated sites like Twitter and YouTube have encouraged direct action and politicised young people in unprecedented numbers. Yet, at the same time, the Web's openness enables hardline states to spy and censor, and extremists to threaten with networks of hate and crippling cyber attacks.

In the third programme of the series, Aleks gives the lowdown on how, for better and for worse, commerce has colonized the web - and reveals how web users are paying for what appear to be 'free' sites and services in hidden ways. Joined by some of the most influential business leaders of today's web, including Eric Schmidt (CEO of Google), Chad Hurley (CEO of YouTube), Bill Gates, Martha Lane Fox and Reed Hastings (CEO of Netflix), Aleks traces how business, with varying degrees of success, has attempted to make money on the web. She tells the inside story of the gold rush years of the dotcom bubble and reveals how retailers such as Amazon learned the lessons. She also charts how, out of the ashes, Google forged the business model that has come to dominate today's web, offering a plethora of highly attractive, overtly free web services, including search, maps and video, that are in fact funded through a sophisticated and highly lucrative advertising system which trades on what we users look for. Aleks explores how web advertising is evolving further to become more targeted and relevant to individual consumers. Recommendation engines, pioneered by retailers such as Amazon, are also breaking down the barriers between commerce and consumer by marketing future purchases to us based on our previous choices. On the surface, the web appears to have brought about a revolution in convenience. But, as companies start to build up databases on our online habits and preferences, Aleks questions what this may mean for our notions of privacy and personal space in the 21st century

Dr Aleks Krotoski concludes her investigation of how the World Wide Web is transforming almost every aspect of our lives. Joined by Facebook founder Mark Zuckerberg, Bill Gates, Al Gore and the neuroscientist Susan Greenfield, Aleks examines the popularity of social networks such as Facebook and asks how they are changing our relationships. And, in a ground-breaking test at University College London, Aleks investigates how the Web may be distracting and overloading our brains.

More than a decade ago, scientists announced that they had produced the first draft of the human genome, the 3.6 billion letters of our genetic code. It was seen as one of the greatest scientific achievements of our age, a breakthrough that would usher in a new age of medicine. Find out how close we are to developing the life-changing treatments that were hoped for". Follow three people, each with a genetic disease, as they go behind the scenes at some of Britain's leading research labs to find out what the sequencing of the human genome has done for them - and the hope this remarkable project offers all of us.

Painted over five centuries ago, Filippo Lippi's nativity is like none other: it shows the birth of Christ in a dark, wooded wilderness. There are no shepherds, kings, ox, ass – there is no Joseph. Its beauty inspired Michelangelo, Leonardo da Vinci and Botticelli. But it also conceals a deeply personal story. It was painted for Cosimo de Medici, a wealthy banker who feared that his money was dragging him straight to hell. The artist's life was equally surprising. One of the most celebrated painters of his day, Filippo Lippi was also a Carmelite friar, but he was no stranger to the temptations of the flesh, to which he frequently yielded. Shortly before painting his Adoration, he caused uproar by seducing a twenty year-old nun. His paintings rejoice not only in divine beauty, but in the beauty of women. In later times, the Adoration's history was interwoven with that of rulers and dictators. It became a bargaining chip after Napoleon's allies seized twenty merchant ships. And in the 20th century, it was hidden by the Nazis in a potassium mine, where specialist american officers, known as Monuments Men, stumbled upon it. they were now told to get it ready to be shipped out. In an unprecedented turn of events they refused. This is the only known case in the whole of the Second World War of American officers refusing an order. It was sent to the National Gallery of Art, but in 1949 Lippi's Adoration was returned to Germany.