The title of Ava DuVernay's extraordinary and galvanizing documentary refers to the 13th Amendment to the Constitution, which reads 'Neither slavery nor involuntary servitude, except as a punishment for crime whereof the party shall have been duly convicted, shall exist within the United States.' The progression from that second qualifying clause to the horrors of mass criminalization and the sprawling American prison industry is laid out by DuVernay with bracing lucidity. With a potent mixture of archival footage and testimony from a dazzling array of activists, politicians, historians, and formerly incarcerated women and men, DuVernay creates a work of grand historical synthesis.

Cities are growing at a faster rate than any other habitat on Earth. They may seem an unlikely place for animals to thrive, but they can be a world of surprising opportunity. Leopards prowl the streets of Mumbai, peregrine falcons hunt amongst New York's skyscrapers, and a million starlings perform spectacular aerial dances over Rome. In Jodhpur, langurs are revered as religious deities and in Harar, locals live in harmony with wild hyenas. Many animals, however, struggle to cope in the urban jungle. As the architects of this environment, can humans choose to build cities that are homes for both them and wildlife?

We all agree lying is shameful. Yet we still deliberately deceive each other constantly. Are our brains wired for lying from a young age? The brains of pathological liars may provide insights. Will technology make it easier for us to be dishonest, or could it someday instantly reveal someone is lying? Perhaps we are deceitful because our limited senses prevent us from seeing the real truth. Scientists say our own memories deceive us, and have managed to implant false memories. Other scientists look for ultimate truth in the subatomic world … only to end up turning reality on its head.

Every year, over a thousand climbers try to reach the summit of Mount Everest, with the annual record for successful attempts currently standing at 633. But of that number, nearly half were Sherpas - the mountain's unsung heroes. Yet the Sherpa community has remained secretive about their nation, culture and experiences living in the shadow of the world's highest mountain. Now, for the first time, they open the door into their world. Without the expertise of the Sherpas, only the hardiest and most skilful climbers would succeed. Every day they risk their lives for the safety of others, yet they seek neither glory nor reward, preferring to stay in the background. Following the stories of four such Sherpas - Phurba, Ngima, Ngima Tenji and Gelu - this film reveals the reality of their daily lives, not just up the mountain, but with their families after they return home.

Is mankind alone, or are there aliens out there, either waiting to be discovered, or on their way to find Earth? Professor Brian Cox spends this episode asking such questions, and what he discovers may raise a few eyebrows. He begins by exploring the human race's efforts to find neighbours in outer space, including the launch of two golden discs containing a greeting from Earth in the 1970s; they are still travelling and are now the most distant man-made objects from the planet. Brian also meets members of the Search for Extra-Terrestrial Intelligence, who have been monitoring radio signals for 50 years without success, before discussing the ingredients needed to make an intelligent civilisation with astrophysicist Dr Frank Drake.

Is God worshipped in other worlds, across the cosmos? How might alien deities differ from our own? The answer may lie buried on Earth. Animal behaviorists are testing elephants and finding them capable of having spiritual thoughts. Artificial intelligence researchers are building enlightened robots that contemplate the divine. Meanwhile, cosmologists are looking for universal equations that could replace God. Have advanced aliens discovered everything there is to know about the universe? Or are they looking to a higher power for answers?