Over a person's lifetime they are likely to be prescribed more than 14,000 pills. Antibiotics, cholesterol lowering tablets, anti-depressants, painkillers, even tablets to extend youth and improve performance in bed. These drugs perform minor miracles day after day, but how much is really known about them? Drug discovery often owes as much to serendipity as to science, and that means much is learnt about how medicines work, or even what they do, when they're taken. By investigating some of the most popular pills people pop, Horizon asks, how much can they be trusted to do what they are supposed to?

The world stood in fear of an emerging new disease that threatened to kill millions. A new flu variant H1N1 had arrived. If this latest pandemic has taught anything, it is just how little is understood about the invisible world of viruses. But that has not stopped scientists trying. Horizon follows the leading researchers from across the world, who are attempting to unravel the many secrets of viruses to understand when and why they kill.

More than a decade ago, scientists announced that they had produced the first draft of the human genome, the 3.6 billion letters of our genetic code. It was seen as one of the greatest scientific achievements of our age, a breakthrough that would usher in a new age of medicine. Find out how close we are to developing the life-changing treatments that were hoped for". Follow three people, each with a genetic disease, as they go behind the scenes at some of Britain's leading research labs to find out what the sequencing of the human genome has done for them - and the hope this remarkable project offers all of us.

Painted over five centuries ago, Filippo Lippi's nativity is like none other: it shows the birth of Christ in a dark, wooded wilderness. There are no shepherds, kings, ox, ass – there is no Joseph. Its beauty inspired Michelangelo, Leonardo da Vinci and Botticelli. But it also conceals a deeply personal story. It was painted for Cosimo de Medici, a wealthy banker who feared that his money was dragging him straight to hell. The artist's life was equally surprising. One of the most celebrated painters of his day, Filippo Lippi was also a Carmelite friar, but he was no stranger to the temptations of the flesh, to which he frequently yielded. Shortly before painting his Adoration, he caused uproar by seducing a twenty year-old nun. His paintings rejoice not only in divine beauty, but in the beauty of women. In later times, the Adoration's history was interwoven with that of rulers and dictators. It became a bargaining chip after Napoleon's allies seized twenty merchant ships. And in the 20th century, it was hidden by the Nazis in a potassium mine, where specialist american officers, known as Monuments Men, stumbled upon it. they were now told to get it ready to be shipped out. In an unprecedented turn of events they refused. This is the only known case in the whole of the Second World War of American officers refusing an order. It was sent to the National Gallery of Art, but in 1949 Lippi's Adoration was returned to Germany.

The story of how the secret of life has been examined through the prism of the most complex organism known - the human body. It begins with attempts to save the lives of gladiators in Ancient Rome, unfolds with the macabre work and near-perfect drawings of Leonardo in the Renaissance, through the idea of the 'life force' of electricity, to the microscopic world of the cell. It reveals how a moral crisis unleashed by work on the nuclear bomb helped trigger a great breakthrough in biology - understanding the structure and workings of DNA.

We now know that the brain - the organ that more than any other makes us human - is one of the wonders of the universe, and yet until the 17th century it was barely studied. The twin sciences of brain anatomy and psychology have offered different visions of who we are. Now these sciences are coming together and in the process have revealed some surprising and uncomfortable truths about what really shapes our thoughts, feelings and desires. And the search to understand how our brains work has also revealed that we are all - whether we realise it or not - carrying out science from the moment we are born.