Everywhere we look in the most hospitable of environments and in the most extreme we find life. On Earth, life exists everywhere we look. Yet we have only ever found life on our planet. How did the stuff of stars come together to create life as we know it? What do we really mean by 'life'? And will unlocking this mystery help us find life elsewhere?

Aliens almost certainly do exist. So why haven't we yet met E.T.? It turns out we're only just developing instruments powerful enough to scan for them, and science sophisticated enough to know where to look. As a result, race is on to find the first intelligent aliens. But what would they look like, and how would they interact with us if we met? The answers may come to us sooner than we imagine, for one leading astronomer believes she may already have heard a hint of their first efforts to communicate

What is the universe made of? If you answered stars, planets, gas and dust, you'd be dead wrong. Thirty years ago, scientists first realized that some unknown dark substance was affecting the way galaxies moved. Today, they think there must be five times our understanding of the universe and the nature of reality itself has drastically changed over the last 100 years - and it's on the verge of another seismic shift. In a 17-mile-long tunnel buried 570 feet beneath the Franco-Swiss border, the world's largest and most powerful atom smasher, the Large Hadron Collider, is powering up. Its goal is nothing less than recreating the first instants of creation, when the universe was unimaginably hot and long-extinct forms of matter sizzled and cooled into stars, planets, and ultimately, us. These incredibly small and exotic particles hold the keys to the greatest mysteries of the universe. What we find could validate our long-held theories about how the world works and what we are made of -- or, all of our notions about the essence of what is real will fall apart.

Everyone from the most simple-minded to the deepest thinking has pondered a question that strikes at the core of our existence: Is there life after death? What happens to the soul after we die? People who have had near-death experiences claim to have visited the other side before getting yanked back into consciousness. Now, some of the brightest minds in science are trying to understand how life can persist beyond the physical and what will it look like. It might be a quantum state based on the fundamental laws of the universe. Ultimately, it is a journey that struggles to decode the most complicated instrument in the universe: the human brain.

It's a mystery mankind has struggled to solve since the beginning of history - is space infinite or might there be great cosmic border where everything ends? Groundbreaking cosmology and state of the art space telescopes, now suggest the Universe has a finite size and a unique shape. If this is true, there must be an edge to the Universe, and beyond that edge, there could exist a world beyond our wildest dreams.

Time is woven into the fabric of the universe as one of the dimensions in which we live our daily lives. But maybe it is only a brain state that we use to piece together events. Could it exist only in our minds? Your sense of time can be totally different than the person next to you. This and other theories illustrate that time is an illusion and does not really exist. The world's top physicists tackle this fundamental question, does time exist, and offer new ways to perceive the physical world.