Spain is found at the crossroads between the Mediterranean and the Atlantic, between Europe and Africa, resulting in diverse landscapes, ancient cultures and magnificent wildlife. It's a hidden Spain missed by many tourists who fail to venture outside the resorts. Worlds within worlds, the medieval towns, to farming communities, desert, mountains and forests with some of the most dramatic and diverse wildlife of the continent.

Ewan McGregor and Charley Boorman, after more than a decade since their last motorbike adventure around the world, will cover 13,000 miles over 100 days through 13 countries. Starting from the city of Ushuaia at the tip of South America, Ewan and Charley travel through the glorious and underexposed landscapes of South and Central America to Los Angeles in the United States in their most challenging expedition to date. In their journey they will use cutting-edge technology on the backs of their prototype electric Harley-Davidsons in order to contribute to the sustainability of the planet.
In the first episode, Ewan McGregor reunites with his best friend Charley Boorman to evaluate what's important in their lives, following a life-threatening accident of Charley.

Episode 3 continues to show the obstacles faced with charging electric bikes in remote places, but Ewan McGregor and Charley Boorman start to learn and evolve their process. The risk of cold temperatures is high but they bravely do it anyway. The duo is having a hard time of it out there but, thankfully, the scenery is absolutely stunning. Heading through Patagonia, Ewan and Charley stay at an eco-lodge in one of the world’s remotest areas with people that live off the grid.

The fourth episode starts off with the two riding through Santa Cruz, Argentina. The plan is to cross over into Chile and then going up into the Andes. Ewan and Charley head through Argentina’s red rock landscape while a member of their team copes with altitude sickness. The duo are well and truly underway and the first signs of all are well is how well the Harleys hold up in challenging conditions. The roads alternate between unforgiving and pleasant and these e-bikes push through effortlessly. As they ride through Chilean Andes, the audience is shown a picturesque view of the beauty of the countryside, an experience which Boorman calls 'magical.'

As the journey continues, there's beauty and danger in equal measure for Charley Boorman and Ewan McGrego. The duo ride their electric Harleys through the exotic and breathtaking Bolivian countryside in a tough ascent. The sixth episode showcases some of the challenges the hosts and the crew face when they scale the terrain. One of the Rivians runs into trouble while sandy roads and a heavy breeze sees Boorman take a tumble. Apart from all the accidents, the chapter also shows some quality work done by UNICEF when it comes to educating and working with the children in Bolivia.
The altitude sickness hits Taylor, their logistics man real bad and McGregor starts feeling it as well. The episode ends with a doctor heading to his hotel room to check up on him.

Laurent Ballesta has yet again challenged himself to a new world record: spend 28 days at a depth of 100 meters to reveal the luxuriant and unknown depths of the Mediterranean.
Because people have been travelling there for thousands of years, this sea is be­lieved to be without secrets. And yet, far below its surface, lie vast unexplored territories, luxurious gardens worthy of the finest tro­pical coral reefs. These natural wonders are inaccessible to the traditional diver, in a twilight zone, between 60 and 120 m, where there’s less than 1% of sunlight. If diving at such depths is always a challenge, staying there is a fan­tasy, a utopia that becomes reality in 'The Deep Med'.