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Nicholas felt enormous pressure to continue the dynasty and expand the empire. He saw his opportunity in the Far East. This brought him into conflict with a rising power, Japan. Russia's disastrous war against Japan prompts civil unrest. The birth of Prince Alexei is incredibly important. He's the long-awaited son that they had hoped so much for. But when Alexei is diagnosed with haemophilia, Siberian mystic Rasputin steps in. He's very good at realizing when something is open that will enable him to increase his power and wealth. The pressure of keeping the secret of Alexei's illness affects the political decisions that Nicky and Alix made for the rest of their reign.

The Romanovs retreat into a bubble of luxury while the czar's forces brutally suppress protests by a starving populace. Rasputin's influence grows, never mind the rumors and scandals. Many people believe Prime minister Peter Stolypin is the last hope of the Romanov Dynasty as reformer-in-chief. He is horrified by the rise of Rasputin. The fight between Stolypin and Rasputin is a battle for influence over Nicholas II. But Stolypin is shot in the Kiev Opera in 1911.

In 1914, Russia entered World War I in response to Austria-Hungary's declaration of war on Russia's ally Serbia. This was fought across multiple fronts while isolated from its allies. The Battle of Tannenberg, where the entire Russian Second Army was annihilated, cast an ominous shadow over the empire's future. The already-existing public distrust of the regime was deepened by the rising costs of the war and rumours of corruption. World War I takes Nicholas to the front. Back home, outrage grows over high casualties and Alexandra and Rasputin's political intrigues.

Nicholas II abdicates, and civil war erupts. In May 1918, a year after the revolution, the Bolsheviks sent Anastasia, Alexei, Tatiana and Olga to join the rest of the family in Ekaterinburg. They're put in the Ipatiev mansion and It's given the name 'The House of Special Purpose.' As pro-royalist forces close in on the house where the Romanovs are imprisoned, the family's fate is sealed.

Trailblazing scientists are making ground-breaking discoveries in the rapidly evolving world of genetic engineering. Technologies like CRISPR are making it possible to quickly and cheaply change the DNA of all living things, including humans. Today, genes can be edited almost as easily as words on a computer screen. This new ability to alter our DNA holds the promise of curing disease , saving threatened species, solving the problem of world hunger and maybe even obtaining human perfection. But will the promise be fulfilled and at what cost?
The ability to gain control of our DNA is ground-breaking and revolutionary but there are varying opinions among scientists as to how the technology should be used responsibly. This documentary follows the science as it progresses at a breakneck speed.

NASA is on a mission to send humans to Mars within just 15 years, but to reach this next frontier of space exploration, experts must discover new technology and cutting-edge science that protects astronauts from the Red Planet's deadliest killers.