Diseases

The world is affected by an obesity epidemic, but why is it that not everyone is succumbing? Medical science has been obsessed with this subject and is coming up with some unexpected answers. As it turns out, it is not all about exercise and diet. At the centre of this programme is a controversial overeating experiment that aims to identify exactly what it is about some people that makes it hard for them to bulk up.

We are in the grip of an allergy epidemic. 50 years ago one in 30 were affected, but in Britain today it is closer to one in three. Why this should be is one of modern medicine's greatest puzzles. In search of answers, Horizon travels round the globe, from the remotest inhabited island to the polluted centres of California and the UK. We meet sufferers and the scientists who have dedicated their lives trying to answer the mystery of why we are becoming allergic to our world.

It is a nightmare that has stalked us for centuries: hordes of human beings transformed into mindless, cannibalistic monsters. Could this civilization-ending nightmare become reality? Scientists have discovered pathogens that turn insects into the walking dead. New strains of viruses are attacking humans every day. Mathematicians have calculated the likelihood of surviving a zombie virus outbreak: they’re not hopeful. Now neuroscientists are discovering how easy it is for us to lose conscious control of our bodies. Are we at risk of becoming puppets? If we were in the middle of a zombie apocalypse, would we even know it?

Placebos come in all shapes and sizes, but they contain no active ingredient. They are the miracle pills that shouldn't really work at all. Now they are being shown to help treat pain, depression and even alleviate some of the symptoms of Parkinson's disease. It seems they're not acting alone. The placebo effect is intertwined with how is did the healthcare. Explores why they work, and how we could all benefit from the hidden power of the placebo.

Around the world, food allergies are surging to near-epidemic levels. Medicine is just beginning to understand why some people react to seemingly harmless foods. Scientists race to understand what's changed in our bodies, while farmers and chefs contend with new challenges.

Dr Chris van Tulleken, Dr Hannah Fry and Michael Mosley examine the latest research and explore some of the big questions about Covid-19 and the pandemic it has created. Michael visits the UK government's high-security laboratory Porton Down, where vaccines are being tested. He also uncovers what the experience of the 2002 SARs epidemic reveals about this one. Both were caused by coronaviruses, but certain key changes to today's virus have allowed it to infect the world, where SARs was contained.