Over a person's lifetime they are likely to be prescribed more than 14,000 pills. Antibiotics, cholesterol lowering tablets, anti-depressants, painkillers, even tablets to extend youth and improve performance in bed. These drugs perform minor miracles day after day, but how much is really known about them? Drug discovery often owes as much to serendipity as to science, and that means much is learnt about how medicines work, or even what they do, when they're taken. By investigating some of the most popular pills people pop, Horizon asks, how much can they be trusted to do what they are supposed to?

The world is affected by an obesity epidemic, but why is it that not everyone is succumbing? Medical science has been obsessed with this subject and is coming up with some unexpected answers. As it turns out, it is not all about exercise and diet. At the centre of this programme is a controversial overeating experiment that aims to identify exactly what it is about some people that makes it hard for them to bulk up.

For centuries scientists have been attempting to come up with an elixir of youth. Now remarkable discoveries are suggesting that ageing is something flexible that can ultimately be manipulated. The scientists are attempting to piece together why we age and more vitally for all of us, what we can do to prevent it. But which theory will prevail? Does the real key to controlling how we age lie with a five-year-old boy with an extraordinary ageing disease or with a self-experimenting Harvard professor? Could one of these breakthroughs really see our lives extend past 120 years?

Horizon explores the strange and wonderful world of illusions – and reveals the tricks they play on our senses and why they fool us. We show how easy it is to trick your sense of taste by changing the colours of food and drink, explain how what you see can change what you hear, and see just how unreliable our sense of colour can be. But all this trickery has a serious purpose. It’s helping scientists to create a new understanding of how our senses work – not as individual senses, but connected together. It holds the intriguing possibility that one sense could be mapped into another.

Horizon uncovers the secret world of our dreams. In a series of cutting-edge experiments and personal stories, we go in search of the science behind this most enduring mystery and ask: where do dreams come from? Do they have meaning? And ultimately, why do we dream? What the film reveals is that much of what we thought we knew no longer stands true. Dreams are not simply wild imaginings but play a significant part in all our lives as they have an impact on our memories, the ability to learn, and our mental health. Most surprisingly, we find nightmares, too, are beneficial and may even explain the survival of our species.

We are in the grip of an allergy epidemic. 50 years ago one in 30 were affected, but in Britain today it is closer to one in three. Why this should be is one of modern medicine's greatest puzzles. In search of answers, Horizon travels round the globe, from the remotest inhabited island to the polluted centres of California and the UK. We meet sufferers and the scientists who have dedicated their lives trying to answer the mystery of why we are becoming allergic to our world.