Magic mushrooms, long considered sacred by the Indigenous Mazatec in Mexico, become the subject of scientific studies measuring the intense effects of its Psilocybin and its potential therapeutic use.
In the second episode, we are introduced to Ben, who’s battled with crippling Obsessive-Compulsive Disorder (OCD) his entire life. When he had his firstborn, Ben’s life became full of panic attacks regarding his son’s safety, and he knew something had to change. Ben signed up for a psilocybin-assisted therapy clinical trial which was testing whether the psychedelic could help people with severe OCD. In the session under the influence of psilocybin, Ben felt decomposed and eventually grew into a tree. While living as a tree, he saw his human self, playing with his child. Though this sounds scary, from Ben’s perspective, it was beautiful. He was one with the universe, seeing himself in the ultimate third-person perspective. Finally, he saw how it could be different if he didn’t let his OCD control him. And several months out, all the symptoms disappeared.
Ben’s story is one of many told in this series, which gives hope that help is right around the corner for the millions who suffer —often in silence— with debilitating mental disorders. But Michael Pollan’s work is showcasing the success stories. Often, even in the most successful trials, psychedelic-assisted therapy only helps up to a third of people enter remission. More frequently, patients are helped —sometimes substantially— but they still suffer with their illnesses and some people aren’t helped at all.

Championed by both therapists and ravers, ecstasy stands out as the first psychedelic likely to become legalized, thanks to passionate advocates.
The episode about 3,4-Methylenedioxymethamphetamine (MDMA), is focused on Multidisciplinary Association for Psychedelic Studies (MAPS) clinical trials treating Post-traumatic stress disorder (PTSD).

To maximize longevity, you might think it’s best to play it safe and stay cozy. But some scientists believe we should do the opposite, as exposure to extreme temperatures can trigger our bodies’ own defenses against the killer diseases of old age. Chris heads for the freezing Arctic with his brothers Liam and Luke to take on the ultimate cold therapy.

Chris turns to longevity doctor Peter Attia to find out how changing his eating habits can help his quest for longevity. Ironically, the answer is to eat no food at all for four long days. If he can bear the hunger, fasting will unlock his body’s own anti-aging powers and give Chris the edge he needs when he tries to hunt for his next meal … by spearfishing off the Great Barrier Reef.

As Chris bulks up for ‘Thor: Love and Thunder’ he needs to build a body that looks right for an immortal god. But, he also wants the kind of muscles that are scientifically proven to help him stay strong and healthy as he grows older in real life. Teaming up with extreme sports guru Ross Edgley, he trains for a grueling 100-foot rope climb challenge, changing him from an ornament into an instrument.

Chris has always worked to keep his body healthy; now it’s time to start looking after his brain. Neurologist Dr. Sharon Sha challenges him to go off-grid into the wilderness without a GPS or map. Teaming up with his buddy, First Nations artist Otis Hope Carey, Chris will need to tune into nature to navigate through Otis’ remote ancestral homeland. The hike stirs up Chris’s most precious memories.