After the murder of his brother Frank, Al Capone is out for revenge against William Dever and the Chicago police. He plots to kill every undercover cop that was in Cicero on the day of Frank’s death. Before he can set his plan in motion, however, Johnny Torrio returns from Italy and reclaims his control of their criminal empire. Torrio forbids Capone from killing cops, fearing it would spark an all-out war. Despite Capone’s personal loss, Torrio returns to a booming business that’s raking in $10 million a month. However, as Torrio and Capone’s empire grows, it becomes harder to keep smaller factions under control. After a small group of Italian mobsters attacks one of Dean O’Banion’s distilleries, O’Banion blames Torrio and decides to end their business partnership. He announces his retirement to Torrio and offers Torrio an opportunity to buy him out. Torrio meets O’Banion at the Seine Brewery on May 19, 1924, with the buyout money. Chicago police raid the brewery and arrest Torrio while letting O’Banion walk free: O’Banion had set the whole thing up. With prior convictions, Torrio serves a mandatory prison sentence but is first released on bail. He vows to kill O’Banion as payback and gives Capone his blessing to kill O’Banion. Capone spends months planning the hit. Capone knows that catching O’Banion off guard is nearly impossible, so he places an order with O’Banion’s flower shop for nearly $20,000 worth of flowers, knowing that O’Banion personally oversees his biggest arrangements. On November 10, 1924, O’Banion works in his shop preparing the flower delivery. Two of Capone’s men enter the shop and fatally gun O’Banion down. Four days later, Chicago’s most powerful Irish gangster is laid to rest in one of the most lavish funerals Chicago has ever seen. More than two dozen cars are required to transport floral arrangements as a crowd of 10,000 mourns the death of the infamous gangster. Torrio and Capone attend the funeral, infuriating O’Banion’s top lieutenants, Hymie Weiss and Bugs Moran. Chaos breaks out as smaller gangs through the city begin a turf war. It’s the beginning of an era of bloodshed in Chicago known as the Beer Wars. Over 300 people are murdered at a rate of 75 to 100 murders a year.

Al Capone moves back to Chicago and takes over two floors of the city's finest hotel, the Lexington. With a thriving business and Chicago politicians in his back pocket, Capone soon reaches a level of celebrity normally reserved for athletes and entertainers. As Capone's profile grows, he begins to indulge in all that the Roaring '20s have to offer, including cocaine. While Capone enjoys his reign at the top of the Chicago underworld, Irish gangster Bugs Moran seeks to take him down as revenge for the deaths of his partners Dean O'Banion and Hymie Weiss. On March 7, 1928, Moran orders a hit on one of Capone's top associates, Jack McGurn, the man who took out Hymie Weiss. McGurn survives but Capone decides to retaliate by taking out Moran and as many of his men as possible - all at once. On February 14, 1929, Capone's men dress as law enforcement and raid the liquor buy. They order Moran's men to face the wall for handcuffing, but while their backs are turned, Capone's men shoot all of them. Firing 70 rounds of ammunition in less than 10 seconds, the assassins carry out the biggest gangland hit in American history that will come to be known as the St. Valentine's Day Massacre. Through a stroke of luck, Moran avoids the massacre, but knows he's been defeated.

After becoming the most powerful mob boss in the country, Al Capone now finds himself locked up in America's newest and harshest maximum security prison: Alcatraz. Prohibition has recently been repealed and one of the Outfit's most important sources of income dries up. With Capone cut off from all communication, his most trusted men, Frank Nitti, Tony Accardo and Paul Ricca, must keep his organization from collapsing. With Americans flocking to theaters by the thousands, the movie business is raking in millions of dollars a month. To take advantage of Hollywood, Nitti recruits Willy Bioff. Acardo breaks into a new racket in Chicago: slot machines. With help from Ricca, Accardo builds a network of slots in Chicago bars, earning up to $20,000 a year. By the end of 1939, the Outfit is bringing in more money than ever before... But new problems start to appear.

Oil theft has become big business in Nigeria. Travel to this Africa's oil-producing region to meet with oil thieves, and follows one farmer's attempt to sue a foreign oil company for poisoning his family's land. The lethal combination of gangs and guns has turned Chicago into a war zone. Visit the city's most dangerous areas.

In the 1980s, ruthless Colombian cocaine barons invaded Miami with a brand of violence unseen in this country since Prohibition-era Chicago - and it put the city on the map. The film is the true story of how Miami became the drug, murder and cash capital of the United States, told by the people who made it all happen.

In less than two years, Al Capone has risen from a humble bookkeeper to second-in-command of Johnny Torrio's criminal empire in Chicago. The empire is worth the modern-day equivalent of $35 million. Capone purchases a home for his family and moves them from New York to Chicago. Torrio and Capone expand their empire from Chicago's South Side to the North Side, which is controlled by Chicago's second largest gang, the Irish. Violence erupts as ruthless Irish gang leader Dean O'Banion protects his territory and bootlegging business from Torrio and Capone.